Paolo Sansoni
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Explore the profile of Paolo Sansoni including associated specialties, affiliations and a list of published articles.
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23
Citations
827
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Recent Articles
1.
Bajwa M, Vita S, Vescovini R, Larsen M, Sansoni P, Terrazzini N, et al.
J Infect Dis
. 2017 Feb;
215(8):1212-1220.
PMID: 28199648
Cytomegalovirus (CMV) infection sometimes causes large expansions of CMV-specific T cells, particularly in older people. This is believed to undermine immunity to other pathogens and to accelerate immunosenescence. While multiple...
2.
Bajwa M, Vita S, Vescovini R, Larsen M, Sansoni P, Terrazzini N, et al.
J Infect Dis
. 2016 Aug;
214(9):1430-1437.
PMID: 27521364
Background: Parallel upregulation of several T-cell effector functions (ie, polyfunctionality) is believed to be critical for the protection against viruses but thought to decrease in large T-cell expansions, in particular...
3.
Vescovini R, Telera A, Pedrazzoni M, Abbate B, Rossetti P, Verzicco I, et al.
PLoS One
. 2016 Mar;
11(3):e0151965.
PMID: 26990192
Human cytomegalovirus (HCMV) imprints the immune system after primary infection, however its effect during chronic infection still needs to be deciphered. In this study we report the variation of blood...
4.
Bucci L, Ostan R, Cevenini E, Pini E, Scurti M, Vitale G, et al.
Aging (Albany NY)
. 2016 Mar;
8(3):510-9.
PMID: 26979133
Within the scenario of an increasing life expectancy worldwide it is mandatory to identify determinants of healthy aging. Centenarian offspring (CO) is one of the most informative model to identify...
5.
Sansoni P, Vescovini R, Fagnoni F, Akbar A, Arens R, Chiu Y, et al.
Exp Gerontol
. 2014 Apr;
55:54-62.
PMID: 24703889
Immunosenescence, defined as the age-associated dysregulation and dysfunction of the immune system, is characterized by impaired protective immunity and decreased efficacy of vaccines. An increasing number of immunological, clinical and...
6.
Terrazzini N, Bajwa M, Vita S, Thomas D, Smith H, Vescovini R, et al.
Exp Gerontol
. 2013 Dec;
54:94-100.
PMID: 24370373
Infection with Cytomegalovirus is associated with accelerated immunosenescence. Expansions of CMV-specific T cell responses have previously been demonstrated to affect the ability of T cells to respond to other infections....
7.
Vescovini R, Fagnoni F, Telera A, Bucci L, Pedrazzoni M, Magalini F, et al.
Age (Dordr)
. 2013 Dec;
36(2):625-40.
PMID: 24318918
Alterations in the circulating CD8+ T cell pool, with a loss of naïve and accumulation of effector/effector memory cells, are pronounced in older adults. However, homeostatic forces that dictate such...
8.
Cabassi C, Taddei S, Cavirani S, Baroni M, Sansoni P, Romani A
Vet J
. 2013 Oct;
198(2):534-7.
PMID: 24084036
The emergence of multidrug resistant (MDR) and extensively drug resistant (XDR) bacteria has become a medical and veterinary problem. Antimicrobial peptides (AMPs) show potential to overcome antibiotic resistance and could...
9.
Solana R, Tarazona R, Aiello A, Akbar A, Appay V, Beswick M, et al.
Immun Ageing
. 2012 Nov;
9(1):23.
PMID: 23114110
Alone among herpesviruses, persistent Cytomegalovirus (CMV) markedly alters the numbers and proportions of peripheral immune cells in infected-vs-uninfected people. Because the rate of CMV infection increases with age in most...
10.
Wills M, Akbar A, Beswick M, Bosch J, Caruso C, Colonna-Romano G, et al.
Immun Ageing
. 2011 Nov;
8(1):10.
PMID: 22035114
The Second International Workshop on CMV & Immunosenescence was held in Cambridge, UK, 2-4th December, 2010. The presentations covered four separate sessions: cytomegalovirus and T cell phenotypes; T cell memory...