Paolo Madeddu
Overview
Explore the profile of Paolo Madeddu including associated specialties, affiliations and a list of published articles.
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Articles
206
Citations
4218
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Recent Articles
1.
Alvino V, Slater S, Qiu Y, Cattaneo M, Mohammed K, Gate S, et al.
Cardiovasc Diabetol
. 2024 Nov;
23(1):397.
PMID: 39501278
Aims: Aging is influenced by genetic determinants and comorbidities, among which diabetes increases the risk for heart failure with preserved ejection fraction. There is no therapy to prevent heart dysfunction...
2.
Short E, Adcock I, Al-Sarireh B, Ager A, Ajjan R, Akbar N, et al.
medRxiv
. 2024 Sep;
PMID: 39281746
Background: Around the world, individuals are living longer, but an increased average lifespan does not always equate to an increased healthspan. With advancing age, the increased prevalence of ageing-related diseases...
3.
Carrabba M, Fagnano M, Ghorbel M, Rapetto F, Su B, De Maria C, et al.
Adv Funct Mater
. 2024 Sep;
34(7).
PMID: 39257639
The availability of grafts to replace small-diameter arteries remains an unmet clinical need. Here, the validated methodology is reported for a novel hybrid tissue-engineered vascular graft that aims to match...
4.
Mohammed K, Madeddu P, Avolio E
Front Cardiovasc Med
. 2024 Jul;
11:1404253.
PMID: 39011492
Cardiovascular disease (CVD) represents the leading cause of mortality and disability all over the world. Identifying new targeted therapeutic approaches has become a priority of biomedical research to improve patient...
5.
Dunn-Davies H, Dudnakova T, Nogara A, Rodor J, Thomas A, Parish E, et al.
Mol Ther Nucleic Acids
. 2024 Apr;
35(2):102173.
PMID: 38617973
Epigenetic processes involving long non-coding RNAs regulate endothelial gene expression. However, the underlying regulatory mechanisms causing endothelial dysfunction remain to be elucidated. Enhancer of zeste homolog 2 (EZH2) is an...
6.
Riu F, Slater S, Garcia E, Rodriguez-Arabaolaza I, Alvino V, Avolio E, et al.
Sci Rep
. 2024 Mar;
14(1):7132.
PMID: 38531961
No abstract available.
7.
Madeddu P, Huang N
Front Cardiovasc Med
. 2023 Dec;
10:1333866.
PMID: 38045911
No abstract available.
8.
Madeddu P
EMBO Mol Med
. 2023 Oct;
15(12):e18680.
PMID: 37840430
Congenital heart disease (CHD) comprises several cardiovascular abnormalities existing from birth. Cardiac defects range from minor asymptomatic lesions to potentially life-threatening situations. Early fetal echocardiography, the gold standard for the...
9.
Gu Y, Avolio E, Alvino V, Thomas A, Herman A, Miller P, et al.
Cardiovasc Diabetol
. 2023 Aug;
22(1):214.
PMID: 37592236
Background: Cardiac steatosis is an early yet overlooked feature of diabetic cardiomyopathy. There is no available therapy to treat this condition. Tyrosine kinase inhibitors (TKIs) are used as first or...
10.
Cattaneo M, Aleksova A, Malovini A, Avolio E, Thomas A, Alvino V, et al.
Cell Death Dis
. 2023 Aug;
14(8):523.
PMID: 37582912
Long-living individuals (LLIs) escape age-related cardiovascular complications until the very last stage of life. Previous studies have shown that a Longevity-Associated Variant (LAV) of the BPI Fold Containing Family B...