Paolo Bazzigaluppi
Overview
Explore the profile of Paolo Bazzigaluppi including associated specialties, affiliations and a list of published articles.
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26
Citations
417
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Recent Articles
1.
Ringuette D, EbrahimAmini A, Sangphosuk W, Aquilino M, Carroll G, Ashley M, et al.
Neurotherapeutics
. 2024 Jan;
21(1):e00298.
PMID: 38241157
Spreading depolarizations (SDs) are an enigmatic and ubiquitous co-morbidity of neural dysfunction. SDs are propagating waves of local field depolarization and increased extracellular potassium. They increase the metabolic demand on...
2.
Yu J, Joo I, Bazzigaluppi P, Koletar M, Cherin E, Stanisz A, et al.
J Cereb Blood Flow Metab
. 2023 Nov;
44(4):461-476.
PMID: 37974304
Notwithstanding recanalization treatments in the acute stage of stroke, many survivors suffer long-term impairments. Physical rehabilitation is the only widely available strategy for chronic-stage recovery, but its optimization is hindered...
3.
Lai A, Bazzigaluppi P, Morrone C, Hill M, Stefanovic B, McLaurin J
Front Neurosci
. 2022 Jul;
16:897206.
PMID: 35812238
Mid-life hypertension is a major risk factor for developing dementia later in life. While anti-hypertensive drugs restore normotension, dementia risk remains above baseline suggesting that brain damage sustained during transient...
4.
EbrahimAmini A, Mylvaganam S, Bazzigaluppi P, Khazaei M, Velumian A, Stefanovic B, et al.
Int J Mol Sci
. 2021 Aug;
22(16).
PMID: 34445364
A normally functioning nervous system requires normal extracellular potassium ion concentration ([K]o). Throughout the nervous system, several processes, including those of an astrocytic nature, are involved in [K]o regulation. In...
5.
Mester J, Bazzigaluppi P, Dorr A, Beckett T, Burke M, McLaurin J, et al.
Theranostics
. 2021 Aug;
11(16):7685-7699.
PMID: 34335958
Mild traumatic brain injury (mTBI), the most common type of brain trauma, frequently leads to chronic cognitive and neurobehavioral deficits. Intervening effectively is impeded by our poor understanding of its...
6.
Bazzigaluppi P, Mester J, Joo I, Weisspapir I, Dorr A, Koletar M, et al.
J Cereb Blood Flow Metab
. 2021 May;
41(10):2756-2768.
PMID: 33969731
Ischemia is one of the most common causes of acquired brain injury. Central to its noxious sequelae are spreading depolarizations (SDs), waves of persistent depolarizations which start at the location...
7.
EbrahimAmini A, Bazzigaluppi P, Aquilino M, Stefanovic B, Carlen P
Neurobiol Dis
. 2020 Nov;
147:105160.
PMID: 33152505
Raised extracellular potassium ion (K) concentration is associated with several disorders including migraine, stroke, neurotrauma and epilepsy. K spatial buffering is a well-known mechanism for extracellular K regulation/distribution. Astrocytic gap...
8.
Morrone C, Bazzigaluppi P, Beckett T, Hill M, Koletar M, Stefanovic B, et al.
Brain
. 2019 Nov;
143(1):359-373.
PMID: 31782760
Failure of Alzheimer's disease clinical trials to improve or stabilize cognition has led to the need for a better understanding of the driving forces behind cognitive decline in the presence...
9.
Bazzigaluppi P, Beckett T, Koletar M, Hill M, Lai A, Trivedi A, et al.
Hypertension
. 2019 Sep;
74(4):1041-1051.
PMID: 31476904
Transient hypertension is a risk factor for Alzheimer disease (AD), but the effects of this interaction on brain vasculature are understudied. Addressing vascular pathology is a promising avenue to potentiate...
10.
Mester J, Bazzigaluppi P, Weisspapir I, Dorr A, Beckett T, Koletar M, et al.
Neuroimage
. 2019 Jan;
192:135-144.
PMID: 30669007
The rapid growth in the use of optogenetics for neuroscience applications is largely driven by two important advantages: highly specific cellular targeting through genetic manipulations; and precise temporal control of...