Paola Brocca
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Explore the profile of Paola Brocca including associated specialties, affiliations and a list of published articles.
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Articles
32
Citations
205
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Recent Articles
1.
Brusco S, Conte G, Corteggio A, Silvestri T, Spitaleri A, Brocca P, et al.
Adv Healthc Mater
. 2024 Sep;
13(32):e2402688.
PMID: 39258393
Antigen delivery via respiratory mucosal surfaces is an interesting needle-free option for vaccination. Nonetheless, it demands for the design of especially tailored formulations. Here, lipid/poly(lactic-co-glycolic) acid (PLGA) hybrid nanoparticles (hNPs)...
2.
Rondelli V, Koutsioubas A, Di Cola E, Fragneto G, Grillo I, Del Favero E, et al.
Int J Biol Macromol
. 2022 Sep;
221:784-795.
PMID: 36099998
Phenylketonuria (PKU) is a metabolic disorder connected to an excess of phenylalanine (Phe) in the blood and tissues, with neurological consequences. The disease's molecular bases seem to be related to...
3.
Grava M, Helmy S, Gimona M, Parisse P, Casalis L, Brocca P, et al.
Biomol Concepts
. 2022 Mar;
13(1):148-155.
PMID: 35312244
Extracellular vesicles (EVs)-mediated communication relies not only on the delivery of complex molecular cargoes as lipids, proteins, genetic material, and metabolites to their target cells but also on the modification...
4.
Rondelli V, Mollica L, Koutsioubas A, Nasir N, Trapp M, Deboever E, et al.
J Colloid Interface Sci
. 2022 Mar;
616:739-748.
PMID: 35247812
Rhamnolipids (RLs) are among the most important biosurfactants produced by microorganisms, and have been widely investigated because of their multiple biological activities. Their action appears to depend on their structural...
5.
Conte G, Costabile G, Baldassi D, Rondelli V, Bassi R, Colombo D, et al.
ACS Appl Mater Interfaces
. 2022 Feb;
14(6):7565-7578.
PMID: 35107987
Inhaled siRNA therapy has a unique potential for treatment of severe lung diseases, such as cystic fibrosis (CF). Nevertheless, a drug delivery system tackling lung barriers is mandatory to enhance...
6.
Perissinotto F, Rondelli V, Senigagliesi B, Brocca P, Almasy L, Bottyan L, et al.
Nanoscale
. 2021 Sep;
13(30):13158.
PMID: 34477799
Correction for 'Structural insights into fusion mechanisms of small extracellular vesicles with model plasma membranes' by Fabio Perissinotto et al., Nanoscale, 2021, 13, 5224-5233, DOI: .
7.
Perissinotto F, Rondelli V, Senigagliesi B, Brocca P, Almasy L, Bottyan L, et al.
Nanoscale
. 2021 Mar;
13(10):5224-5233.
PMID: 33687046
Extracellular vesicles (EVs) are a potent intercellular communication system. Such small vesicles transport biomolecules between cells and throughout the body, strongly influencing the fate of recipient cells. Due to their...
8.
Brocca P, Saponaro A, Introini B, Rondelli V, Pannuzzo M, Raciti D, et al.
Langmuir
. 2019 Nov;
35(49):16087-16100.
PMID: 31693380
Protein uptake at the interface of a millimeter-sized air bubble in water is investigated by a recently developed differential interferometric technique. The technique allows the study of capillary waves with...
9.
Costabile G, Provenzano R, Azzalin A, Scoffone V, Chiarelli L, Rondelli V, et al.
Nanomedicine
. 2019 Nov;
23:102113.
PMID: 31669084
C109 is a potent but poorly soluble FtsZ inhibitor displaying promising activity against Burkholderia cenocepacia, a high-risk pathogen for cystic fibrosis (CF) sufferers. To harness C109 for inhalation, we developed...
10.
Di Cola E, Cantu L, Brocca P, Rondelli V, Fadda G, Canelli E, et al.
Colloids Surf B Biointerfaces
. 2019 Sep;
183:110439.
PMID: 31473410
We propose novel oil-in-water nanoemulsions (O/W NEs) including PEGylated surfactants and chitosan, showing good biocompatibility and optimization for nasal administration of drugs or vaccines. The transmucosal route has been shown...