Paola Alejandra Fiorani Celedon
Overview
Explore the profile of Paola Alejandra Fiorani Celedon including associated specialties, affiliations and a list of published articles.
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23
Citations
228
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Recent Articles
1.
Freitas N, Campos D, Ferreira R, Jesus F, Silva A, Mota C, et al.
Am J Trop Med Hyg
. 2024 Oct;
112(1):89-95.
PMID: 39471517
Chagas disease (CD), a neglected tropical disease caused by Trypanosoma cruzi, is a significant public health issue particularly in Latin America, affecting millions worldwide. Diagnosis is a challenge owing to...
2.
Mattar S, Celedon P, Leony L, de Carvalho Medrado Vasconcelos L, Sampaio D, Marchini F, et al.
Diagnostics (Basel)
. 2024 Jul;
14(14).
PMID: 39061652
COVID-19 laboratory diagnosis primarily relies on molecular tests, highly sensitive during early infection stages with high viral loads. As the disease progresses, sensitivity decreases, requiring antibody detection. Since the beginning...
3.
Fontes N, Habib F, Leony L, Freitas N, Silva A, Dantas-Torres F, et al.
Parasit Vectors
. 2024 Jul;
17(1):305.
PMID: 39010122
Background: Chagas disease (CD), a neglected parasitic disease caused by Trypanosoma cruzi, poses a significant health threat in Latin America and has emerged globally because of human migration. Trypanosoma cruzi...
4.
Pavan T, Leony L, Souza W, Santos E, Daltro R, Freitas N, et al.
Folia Parasitol (Praha)
. 2024 Mar;
71.
PMID: 38526232
Chagas disease (CD) is a neglected disease caused by Trypanosoma cruzi Chagas, 1909. Causative treatment can be achieved with two drugs: benznidazole or Nifurtimox. There are some gaps that hinder...
5.
Serrano I, Ribeiro G, Santos R, Cruz J, Lanza F, Santos E, et al.
Am J Trop Med Hyg
. 2024 Feb;
110(4):669-676.
PMID: 38412539
Chagas disease (CD) is caused by the protozoan Trypanosoma cruzi, which leads to a spectrum of clinical presentations that range from asymptomatic to severe cardiac involvement. The host immune response...
6.
Soares N, Barreto N, Farias M, Oliveira C, Araujo W, de Souza J, et al.
Pathogens
. 2023 Oct;
12(10).
PMID: 37887738
Chagas disease (CD), caused by the parasite , is a neglected tropical disease with life-threatening implications. In this study, we conducted a seroepidemiological survey to determine the prevalence and clinical...
7.
Daltro R, Santos E, Silva A, Freitas N, Leony L, Vasconcelos L, et al.
PLoS Negl Trop Dis
. 2022 Nov;
16(11):e0010944.
PMID: 36441769
Background: Chagas disease (CD) is caused by Trypanosoma cruzi. The chronic phase of CD is characterized by the presence of IgG anti-T. cruzi antibodies; and diagnosis is performed by serological...
8.
Santos E, Silva A, Freitas N, Leony L, Daltro R, de Souza Teles Santos C, et al.
Front Med (Lausanne)
. 2022 Mar;
9:852864.
PMID: 35330587
Chagas disease (CD) is among the top 10 causes of inability to blood donation. Blood donation centers screen for anti- antibodies using highly sensitive immunoenzymatic (ELISA) or chemiluminescent methods, which...
9.
Freitas N, Santos E, Leony L, Silva A, Daltro R, de Carvalho Medrado Vasconcelos L, et al.
PLoS Negl Trop Dis
. 2022 Mar;
16(3):e0010290.
PMID: 35275913
Background: Enzyme-linked immunosorbent assays (ELISA) are generally the chosen test for Chagas disease (CD) diagnosis; however, its performance depends on the antigen preparation adsorbed to the solid phase, which may...
10.
Celedon P, Leony L, Oliveira U, Freitas N, Silva A, Daltro R, et al.
Biosensors (Basel)
. 2021 Aug;
11(8).
PMID: 34436091
The performance of an immunoassay relies on antigen-antibody interaction; hence, antigen chemical stability and structural integrity are paramount for an efficient assay. We conducted a functional, thermostability and long-term stability...