Pamela McCombe
Overview
Explore the profile of Pamela McCombe including associated specialties, affiliations and a list of published articles.
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65
Citations
1098
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Recent Articles
1.
Toscano S, Spelman T, Ozakbas S, Alroughani R, Chisari C, Lo Fermo S, et al.
Neurotherapeutics
. 2025 Feb;
22(2):e00552.
PMID: 39965993
Predicting long-term prognosis and choosing the appropriate therapeutic approach in patients with Multiple Sclerosis (MS) at the time of diagnosis is crucial in view of a personalized medicine. We investigated...
2.
Dhondt R, Dedja K, Aerts S, Van Wijmeersch B, Kalincik T, Reddel S, et al.
Comput Methods Programs Biomed
. 2025 Feb;
263:108624.
PMID: 39965473
Background: Prognostic machine learning research in multiple sclerosis has been mainly focusing on black-box models predicting whether a patients' disability will progress in a fixed number of years. However, as...
3.
Gillinder L, Craig D, Powell T, Walsh S, Phamnguyen J, Wilson I, et al.
Seizure
. 2025 Jan;
125:73-78.
PMID: 39813747
Objectives: There have been conflicting reports about the frequency of neural autoantibodies in epilepsy cohorts, which is confounded by the lack of clear distinction of epilepsy from acute symptomatic seizures...
4.
Gillinder L, Powell T, Craig D, Walsh S, Gillis D, McCombe P
Epilepsy Behav
. 2024 Dec;
163:110179.
PMID: 39673990
Objective: Anti-GAD65 antibodies have been identified in people with epilepsy for many years, but their pathophysiological relevance is still debated. Susceptibility to autoimmune disease has been associated with Human Leukocyte...
5.
Roos I, Sharmin S, Malpas C, Ozakbas S, Lechner-Scott J, Hodgkinson S, et al.
Mult Scler
. 2024 Aug;
30(9):1163-1175.
PMID: 39087208
Background: Comparisons between cladribine and other potent immunotherapies for multiple sclerosis (MS) are lacking. Objectives: To compare the effectiveness of cladribine against fingolimod, natalizumab, ocrelizumab and alemtuzumab in relapsing-remitting MS....
6.
Lal A, Foong Y, Sanfilippo P, Spelman T, Rath L, Levitz D, et al.
J Neurol
. 2024 Jun;
271(9):5813-5824.
PMID: 38935148
Background: The COVID-19 pandemic raised concern amongst clinicians that disease-modifying therapies (DMT), particularly anti-CD20 monoclonal antibodies (mAb) and fingolimod, could worsen COVID-19 in people with multiple sclerosis (pwMS). This study...
7.
Bassetti C, Accorroni A, Arnesen A, Basri H, Berger T, Berlit P, et al.
Eur J Neurol
. 2024 Mar;
31(6):e16237.
PMID: 38545838
Background And Purpose: In the coming decades, the world will face an increasing burden of neurological disorders (ND) and an urgent need to promote brain health. These challenges contrast with...
8.
Riley N, Drudge C, Nelson M, Haltner A, Barnett M, Broadley S, et al.
Ther Adv Neurol Disord
. 2024 Mar;
17:17562864241239453.
PMID: 38525490
Background: Evidence from network meta-analyses (NMAs) and real-world propensity score (PS) analyses suggest monoclonal antibodies (mAbs) offer a therapeutic advantage over currently available oral therapies and, therefore, warrant consideration as...
9.
Ullah Z, Zafar A, Ishaq H, Umar Z, Khan A, Badar Y, et al.
J Med Case Rep
. 2024 Mar;
18(1):137.
PMID: 38444009
Background: Klippel-Feil syndrome is a rare congenital bone disorder characterized by an abnormal fusion of two or more cervical spine vertebrae. Individuals with Klippel-Feil syndrome exhibit diverse clinical manifestations, including...
10.
Lee A, Henderson R, Aylward J, McCombe P
Int J Mol Sci
. 2024 Feb;
25(3).
PMID: 38339149
Many pathogenetic mechanisms have been proposed for amyotrophic lateral sclerosis (ALS). Recently, there have been emerging suggestions of a possible role for the gut microbiota. Gut microbiota have a range...