Pamela M Odorizzi
Overview
Explore the profile of Pamela M Odorizzi including associated specialties, affiliations and a list of published articles.
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18
Citations
4230
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Recent Articles
1.
Aggarwal A, Odorizzi P, Brodbeck J, van Buuren N, Moon C, Chang S, et al.
JHEP Rep
. 2023 Mar;
5(4):100664.
PMID: 36908748
Background & Aims: Patterns of liver HBV antigen expression have been described but not quantified at single-cell resolution. We applied quantitative techniques to liver biopsies from individuals with chronic hepatitis...
2.
Pan D, Odorizzi P, Schoenichen A, Abdelghany M, Chen S, Osinusi A, et al.
Commun Med (Lond)
. 2023 Jan;
3(1):2.
PMID: 36596885
Background: Remdesivir (RDV) is an intravenous antiviral with activity against SARS-CoV-2 for treatment of hospitalized COVID-19 patients with moderate-to-severe disease. Biomarkers associated with clinical outcomes have been identified for COVID-19,...
3.
McCarthy E, Odorizzi P, Lutz E, Smullin C, Tenvooren I, Stone M, et al.
Cell Rep
. 2022 May;
39(7):110815.
PMID: 35584677
Although generating high neutralizing antibody levels is a key component of protective immunity after acute viral infection or vaccination, little is known about why some individuals generate high versus low...
4.
Pauken K, Godec J, Odorizzi P, Brown K, Yates K, Ngiow S, et al.
Cell Rep
. 2020 Jul;
31(13):107827.
PMID: 32610128
The PD-1 pathway regulates dysfunctional T cells in chronic infection and cancer, but the role of this pathway during acute infection remains less clear. Here, we demonstrate that PD-1 signals...
5.
Odorizzi P, Jagannathan P, McIntyre T, Budker R, Prahl M, Auma A, et al.
Sci Transl Med
. 2018 Oct;
10(463).
PMID: 30333241
Malaria remains a significant cause of morbidity and mortality worldwide, particularly in infants and children. Some studies have reported that exposure to malaria antigens in utero results in the development...
6.
Deeks S, Odorizzi P, Sekaly R
J Clin Invest
. 2016 Dec;
127(1):103-105.
PMID: 27941242
While antiretroviral therapy (ART) has improved the quality of life and increased the life span of many HIV-infected individuals, this therapeutic strategy has several limitations, including a lack of efficacy...
7.
Pauken K, Sammons M, Odorizzi P, Manne S, Godec J, Khan O, et al.
Science
. 2016 Oct;
354(6316):1160-1165.
PMID: 27789795
Blocking Programmed Death-1 (PD-1) can reinvigorate exhausted CD8 T cells (T) and improve control of chronic infections and cancer. However, whether blocking PD-1 can reprogram T into durable memory T...
8.
Odorizzi P, Feeney M
Trends Mol Med
. 2016 Sep;
22(10):877-888.
PMID: 27614925
Pregnancy-associated malaria, including placental malaria, causes significant morbidity and mortality worldwide. Recently, it has been suggested that in utero exposure of the fetus to malaria antigens may negatively impact the...
9.
Bengsch B, Johnson A, Kurachi M, Odorizzi P, Pauken K, Attanasio J, et al.
Immunity
. 2016 Aug;
45(2):358-73.
PMID: 27496729
Dynamic reprogramming of metabolism is essential for T cell effector function and memory formation. However, the regulation of metabolism in exhausted CD8(+) T (Tex) cells is poorly understood. We found...
10.
Barnett B, Staupe R, Odorizzi P, Palko O, Tomov V, Mahan A, et al.
J Immunol
. 2016 Jul;
197(4):1017-22.
PMID: 27430722
The role of Ab and B cells in preventing infection is established. In contrast, the role of B cell responses in containing chronic infections remains poorly understood. IgG2a (IgG1 in...