Palak R Parekh
Overview
Explore the profile of Palak R Parekh including associated specialties, affiliations and a list of published articles.
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Articles
12
Citations
290
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0
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Recent Articles
1.
Parekh P, Botting G, Thurber D, Boruszczak M, Murphy W, Bertenshaw G
Tumour Biol
. 2022 Dec;
44(1):249-267.
PMID: 36502357
Background: Non-small cell lung cancer (NSCLC) is a leading cause of cancer deaths. Current companion diagnostics use driver mutation sequencing to select patients for molecularly targeted agents (MTA), even though...
2.
Parekh P, Solano-Gonzalez E, Martins M, Ma X, Tighe K, Casildo A, et al.
Cancers (Basel)
. 2021 Aug;
13(16).
PMID: 34439340
Treatment options are rather limited for gastrointestinal cancer patients whose disease has disseminated into the intra-abdominal cavity. Here, we designed pre-clinical studies to evaluate the potential application of chemopotentiation by...
3.
Parekh P, Choudhuri R, Weyemi U, Martin O, Bonner W, Redon C
Cancer Med
. 2016 Jun;
5(8):1731-41.
PMID: 27339860
The development of novel cancer treatments is a challenging task, partly because results from model systems often fail to predict drug efficacy in humans, and also tumors are often inaccessible...
4.
Weyemi U, Redon C, Choudhuri R, Aziz T, Maeda D, Boufraqech M, et al.
Nat Commun
. 2016 Feb;
7:10711.
PMID: 26876487
The epithelial-mesenchymal transition (EMT), considered essential for metastatic cancer, has been a focus of much research, but important questions remain. Here, we show that silencing or removing H2A.X, a histone...
5.
Chang E, Parekh P, Yang Q, Nguyen D, Carrier F
Oncotarget
. 2016 Jan;
7(9):10578-93.
PMID: 26824423
The heterogenous ribonucleoprotein A18 (hnRNP A18) promotes tumor growth by coordinating the translation of selected transcripts associated with proliferation and survival. hnRNP A18 binds to and stabilizes the transcripts of...
6.
Nguyen D, Parekh P, Chang E, Sharma N, Carrier F
Radiat Res
. 2015 Jul;
184(2):151-60.
PMID: 26207686
Whole-abdominal radiotherapy (WART) is a primary method for managing gastrointestinal cancers that have disseminated into intra-abdominal tissues. While effective, this approach is limited because of the increased toxicity to normal...
7.
Weyemi U, Redon C, Aziz T, Choudhuri R, Maeda D, Parekh P, et al.
Radiat Res
. 2015 Feb;
183(3):262-70.
PMID: 25706776
Human exposure to ionizing radiation from medical procedures has increased sharply in the last three decades. Recent epidemiological studies suggest a direct relationship between exposure to ionizing radiation and health...
8.
Weyemi U, Redon C, Aziz T, Choudhuri R, Maeda D, Parekh P, et al.
Proc Natl Acad Sci U S A
. 2015 Feb;
112(7):2121-6.
PMID: 25646414
Ataxia telangiectasia (A-T), a rare autosomal recessive disorder characterized by progressive cerebellar degeneration and a greatly increased incidence of cancer among other symptoms, is caused by a defective or missing...
9.
Weyemi U, Redon C, Parekh P, Dupuy C, Bonner W
Anticancer Agents Med Chem
. 2012 Aug;
13(3):502-14.
PMID: 22931418
Reactive oxygen species (ROS) form a class of molecules with both positive and negative impacts on cellular health. Negatively, ROS may react with cellular constituents including proteins, lipids, and DNA...
10.
Redon C, Weyemi U, Parekh P, Huang D, Burrell A, Bonner W
Biochim Biophys Acta
. 2012 Mar;
1819(7):743-56.
PMID: 22430255
Chromatin is a dynamic complex of DNA and proteins that regulates the flow of information from genome to end product. The efficient recognition and faithful repair of DNA damage, particularly...