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Paige E Allen

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Articles 6
Citations 34
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Recent Articles
1.
Allen P, Adcox H, Siff T, Gupta S, Hunt J, Carlyon J
Infect Immun . 2025 Feb; 93(3):e0055924. PMID: 39976440
Cullin-1 (Cul1), a cullin-RING ubiquitin ligase component, represses c-MYC activity in the nucleus. causes the potentially fatal rickettsiosis, scrub typhus. The obligate intracellular bacterium encodes an arsenal of ankyrin repeat-containing...
2.
Adcox H, Hunt J, Allen P, Siff T, Rodino K, Ottens A, et al.
Nat Commun . 2024 Sep; 15(1):8069. PMID: 39277599
How intracellular bacteria subvert the major histocompatibility complex (MHC) class I pathway is poorly understood. Here, we show that the obligate intracellular bacterium Orientia tsutsugamushi uses its effector protein, Ank5,...
3.
Hart T, Sonnert N, Tang X, Chaurasia R, Allen P, Hunt J, et al.
Cell . 2024 Jun; 187(15):4113-4127.e13. PMID: 38876107
Vector-borne diseases are a leading cause of death worldwide and pose a substantial unmet medical need. Pathogens binding to host extracellular proteins (the "exoproteome") represents a crucial interface in the...
4.
Mattern J, Gemmell A, Allen P, Mathers K, Regnault T, Stansfield B
J Dev Orig Health Dis . 2023 Mar; 14(3):321-324. PMID: 36861270
Background: Intrauterine growth restriction (IUGR) exerts a negative impact on developing cardiomyocytes and emerging evidence suggests activation of oxidative stress pathways plays a key role in this altered development. Here,...
5.
Allen P, Noland R, Martinez J
Cell Microbiol . 2021 Aug; 23(11):e13390. PMID: 34464019
Rickettsia conorii is a Gram-negative, cytosolic intracellular bacterium that has classically been investigated in terms of endothelial cell infection. However, R. conorii and other human pathogenic Rickettsia species have evolved...
6.
Kristof M, Allen P, Yutzy L, Thibodaux B, Paddock C, Martinez J
Pathogens . 2021 Mar; 10(2). PMID: 33669499
are significant sources of tick-borne diseases in humans worldwide. In North America, two species in the spotted fever group of have been conclusively associated with disease of humans: , the...
7.
Allen P, Martinez J
Pathogens . 2020 Aug; 9(8). PMID: 32731350
Lipids are a broad group of molecules required for cell maintenance and homeostasis. Various intracellular pathogens have developed mechanisms of modulating and sequestering host lipid processes for a large array...