Padma S Rajagopal
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Explore the profile of Padma S Rajagopal including associated specialties, affiliations and a list of published articles.
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13
Citations
309
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Recent Articles
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Sanghvi N, Calvo-Alcaniz C, Rajagopal P, Scalera S, Canu V, Sinha S, et al.
Sci Adv
. 2024 Dec;
10(49):eadn0220.
PMID: 39642223
Metastasis is a leading cause of cancer-related deaths, yet understanding how metastatic tumors adapt from their origin to their target tissues remains a fundamental challenge. To address this, we assessed...
3.
Agrawal P, Jain N, Gopalan V, Timon A, Singh A, Rajagopal P, et al.
iScience
. 2024 May;
27(5):109752.
PMID: 38699227
Breast cancers (BRCA) exhibit substantial transcriptional heterogeneity, posing a significant clinical challenge. The global transcriptional changes in a disease context, however, are likely mediated by few key genes which reflect...
4.
Sanghvi N, Calvo-Alcaniz C, Rajagopal P, Scalera S, Canu V, Sinha S, et al.
bioRxiv
. 2023 Dec;
PMID: 38076973
Metastasis is a leading cause of cancer-related deaths, yet understanding how metastatic tumors adapt from their origin to target tissues is challenging. To address this, we assessed whether primary and...
5.
Agrawal P, Jain N, Gopalan V, Timon A, Singh A, Rajagopal P, et al.
bioRxiv
. 2023 Jul;
PMID: 37425784
Breast cancers exhibit substantial transcriptional heterogeneity, posing a significant challenge to the prediction of treatment response and prognostication of outcomes. Especially, translation of TNBC subtypes to the clinic remains a...
6.
Dinstag G, Shulman E, Elis E, Ben-Zvi D, Tirosh O, Maimon E, et al.
Med
. 2022 Dec;
4(1):15-30.e8.
PMID: 36513065
Background: Precision oncology is gradually advancing into mainstream clinical practice, demonstrating significant survival benefits. However, eligibility and response rates remain limited in many cases, calling for better predictive biomarkers. Methods:...
7.
Crawford D, Sinha S, Nair N, Ryan B, Barnholtz-Sloan J, Mount S, et al.
Cancers (Basel)
. 2022 Dec;
14(23).
PMID: 36497367
Cancer occurs more frequently in men while autoimmune diseases (AIDs) occur more frequently in women. To explore whether these sex biases have a common basis, we collected 167 AID incidence...
8.
Nair N, Cheng K, Naddaf L, Sharon E, Pal L, Rajagopal P, et al.
Sci Adv
. 2022 Aug;
8(31):eabj7176.
PMID: 35921407
Cancer is a predominant disease across animals. We applied a comparative genomics approach to systematically characterize genes whose conservation levels correlate positively (PC) or negatively (NC) with cancer resistance estimates...
9.
Kar S, Considine D, Tyrer J, Plummer J, Chen S, Dezem F, et al.
HGG Adv
. 2021 Jul;
2(3).
PMID: 34317694
Familial, sequencing, and genome-wide association studies (GWASs) and genetic correlation analyses have progressively unraveled the shared or pleiotropic germline genetics of breast and ovarian cancer. In this study, we aimed...
10.
Pividori M, Rajagopal P, Barbeira A, Liang Y, Melia O, Bastarache L, et al.
Sci Adv
. 2020 Sep;
6(37).
PMID: 32917697
Large-scale genomic and transcriptomic initiatives offer unprecedented insight into complex traits, but clinical translation remains limited by variant-level associations without biological context and lack of analytic resources. Our resource, PhenomeXcan,...