P W Gout
Overview
Explore the profile of P W Gout including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
54
Citations
841
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Lo M, Ling V, Low C, Wang Y, Gout P
Curr Oncol
. 2010 Jun;
17(3):9-16.
PMID: 20567622
Pancreatic cancer is an aggressive, drug-resistant disease; its first-line chemotherapeutic, gemcitabine, is only marginally effective. Intracellular depletion of glutathione, a major free-radical scavenger, has been associated with growth arrest and...
2.
Lo M, Ling V, Wang Y, Gout P
Br J Cancer
. 2008 Jul;
99(3):464-72.
PMID: 18648370
The x(c)(-) cystine transporter enhances biosynthesis of glutathione, a tripeptide thiol important in drug resistance and cellular defense against oxidative stress, by enabling cellular uptake of cystine, a rate-limiting precursor....
3.
Ueda E, Gout P, Morganti L
J Chromatogr A
. 2003 Mar;
988(1):1-23.
PMID: 12647817
Since immobilized metal ion affinity chromatography (IMAC) was first introduced, several variants of this method and many other metal affinity-based techniques have been devised. IMAC quickly established itself as a...
4.
Gout P, Buckley A, Simms C, Bruchovsky N
Leukemia
. 2001 Oct;
15(10):1633-40.
PMID: 11587223
Although cyst(e)ine is nutritionally a non-essential amino acid, lymphoid cells cannot synthesize it, rendering their growth dependent on uptake of cyst(e)ine from their microenvironment. Accordingly, we previously suggested that the...
5.
Ueda E, Gout P, Morganti L
J Chromatogr A
. 2001 Aug;
922(1-2):165-75.
PMID: 11486861
A novel, two-step preparative technique is described for the purification of authentic recombinant human prolactin (rhPRL) secreted into the periplasm of transformed Escherichia coli cells. The first step is based...
6.
Zhang M, Blake M, Gout P, Buckley D, Buckley A
Cell Growth Differ
. 1999 Dec;
10(11):759-67.
PMID: 10593652
Previously, we reported that prolactin (PRL)-dependent Nb2 lymphoma cells exhibit an aberrant heat shock response because of cysteine protease-mediated fragmentation of the heat shock transcription factor (HSF). Moreover, exposure of...
7.
Krumenacker J, Montgomery D, Buckley D, Gout P, Buckley A
Endocrine
. 1999 Apr;
9(3):313-20.
PMID: 10221598
Previously, we reported that activation of the human prolactin receptor (PRLR) produced a protein phosphorylation pattern strikingly similar to that provoked by Concanavalin A (Con A), an activator of the...
8.
Too C, Lee C, Sangster S, Gout P
Cancer Genet Cytogenet
. 1999 Apr;
110(2):115-23.
PMID: 10214359
Cultured rat pre-T Nb2 lymphoma cell lines have provided a useful model for tumor progression of T-cell cancers. Comparative analysis of the non-metastatic, prolactin (PRL)-dependent parental Nb2-U17 line and its...
9.
Bode A, Liang H, Green E, Meyer T, Buckley D, Norris A, et al.
Free Radic Biol Med
. 1999 Jan;
26(1-2):136-47.
PMID: 9890649
Analysis of cultured rat "Nb2 lymphoma" cell lines, showing different degrees of malignant progression, can lead to identification of phenotypic changes associated with this phenomenon in T-cell cancers. In the...
10.
Krumenacker J, Buckley D, Leff M, McCormack J, de Jong G, Gout P, et al.
Endocrine
. 1998 Dec;
9(2):163-70.
PMID: 9867250
Lactogen-dependent Nb2 lymphoma cells, widely employed for studying prolactin (PRL) mitogenic mechanisms, are also useful for investigations of apoptosis in T-lineage lymphocytes. Utilizing PRL-dependent Nb2-11 cultures, apoptosis-regulatory genes were evaluated...