P T Curtin
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Explore the profile of P T Curtin including associated specialties, affiliations and a list of published articles.
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10
Citations
194
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Recent Articles
1.
Madan A, Lin C, Wang Z, Curtin P
Blood Cells Mol Dis
. 2003 Apr;
30(1):82-9.
PMID: 12667989
Erythropoietin (Epo) autocrine stimulation has been implicated in erythroleukemia. To develop a model of Epo autocrine stimulation, we made transgenic mice using a construct that linked the human Epo gene...
2.
Hayes-Lattin B, Curtin P, Fleming W, Leis J, Stepan D, Schubach S, et al.
Bone Marrow Transplant
. 2002 Sep;
30(5):279-85.
PMID: 12209349
AL amyloidosis is a plasma cell disorder in which tissue deposition of immunoglobulin light chains leads to organ dysfunction. Recent reports of high-dose therapy with autologous stem cell transplantation for...
3.
Emery S, Capra W, Cooper D, Mitsuyasu R, Kovacs J, Vig P, et al.
J Infect Dis
. 2000 Jul;
182(2):428-34.
PMID: 10915072
We collected human immunodeficiency virus (HIV) disease progression, survival, most recent CD4 cell count, and plasma HIV RNA levels from patients (n=157) who participated in randomized clinical trials of interleukin...
4.
Kochling J, Curtin P, Madan A
Br J Haematol
. 1999 Jan;
103(4):960-8.
PMID: 9886307
Human erythropoietin (Epo) gene expression is inducible by hypoxia or anaemia in the kidney and liver. Previous transgenic mouse experiments have demonstrated that sequences required for Epo gene induction in...
5.
Madan A, Lin C, Hatch 2nd S, Curtin P
Blood
. 1995 May;
85(10):2735-41.
PMID: 7742534
Erythropoietin (Epo) gene expression in kidney and liver is inducible by anemia. To localize the sequences necessary for regulated expression of the Epo gene, we constructed transgenic mice containing five...
6.
Madan A, Curtin P
Proc Natl Acad Sci U S A
. 1993 May;
90(9):3928-32.
PMID: 8387202
Erythropoietin (Epo) synthesis increases in response to hypoxia. The hepatoma cell line Hep 3B produces low basal levels of Epo mRNA which increase markedly with hypoxia. To define the sequences...
7.
Liu D, Chang J, Moi P, Liu W, Kan Y, Curtin P
Proc Natl Acad Sci U S A
. 1992 May;
89(9):3899-903.
PMID: 1570310
The beta-globin locus control region (LCR) consists of four erythroid-specific DNase I-hypersensitive sites, which are necessary for high-level expression of the beta-like globin genes in erythroid tissues. One of these...
8.
Curtin P, Liu D, Liu W, Chang J, Kan Y
Proc Natl Acad Sci U S A
. 1989 Sep;
86(18):7082-6.
PMID: 2780563
Several lines of evidence suggest that erythroid-specific DNase I hypersensitive sites (HS) located far upstream of the human beta-globin gene are important in regulating beta-globin gene expression. We used the...
9.
10.
Curtin P, Kan Y
Blood
. 1988 Mar;
71(3):766-70.
PMID: 3345345
We have previously described an English family with gamma delta beta-thalassemia in which a large deletion stops 25 kilobases (kb) upstream from the beta-globin gene locus, and yet the beta-globin...