P S MacLean
Overview
Explore the profile of P S MacLean including associated specialties, affiliations and a list of published articles.
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19
Citations
360
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Recent Articles
1.
Foright R, Presby D, Sherk V, Kahn D, Checkley L, Giles E, et al.
Physiol Behav
. 2018 Feb;
188:86-93.
PMID: 29382563
Weight regain after weight loss is one of the most significant challenges to successful obesity treatment. Regular exercise has long been touted as a strategy for weight loss maintenance, but...
2.
Rudolph M, Young B, Lemas D, Palmer C, Hernandez T, Barbour L, et al.
Int J Obes (Lond)
. 2016 Nov;
41(4):510-517.
PMID: 27876761
Background/objectives: Excessive infant weight gain in the first 6-month of life is a powerful predictor of childhood obesity and related health risks. In mice, omega-6 fatty acids (FAs) serve as...
3.
MacLean P, Higgins J, Giles E, Sherk V, Jackman M
Obes Rev
. 2015 Jan;
16 Suppl 1:45-54.
PMID: 25614203
Weight regain after weight loss is a substantial challenge in obesity therapeutics. Dieting leads to significant adaptations in the homeostatic system that controls body weight, which promotes overeating and the...
4.
Strohacker K, McCaffery J, MacLean P, Wing R
Int J Obes (Lond)
. 2013 Jun;
38(3):388-96.
PMID: 23801147
Numerous laboratory studies involving both animal and human models indicate that weight loss induces changes in leptin, ghrelin and insulin sensitivity, which work to promote weight regain. It is unclear,...
5.
MacLean P, Richards M, Williams M, Collins P, Liesner R, Keeling D, et al.
Haemophilia
. 2010 Nov;
17(2):282-7.
PMID: 21070501
With the advent of modern factor replacement therapy the most important remaining obstacle to successful treatment in haemophilia A is the development of inhibitory antibodies against Facto VIII (FVIII). This...
6.
MacLean P, Parker A, McQuaker I, Clark A, Farrell E, Douglas K
Bone Marrow Transplant
. 2007 Jul;
40(7):665-9.
PMID: 17646841
Stem cell dose is important in determining rate of engraftment following autograft. We show closer correlation with haematopoietic reconstitution when the CD34+ cell dose is calculated using ideal (IBW) rather...
7.
MacLean P, Tait R, Rumley A, McMahon A, Lowe G
J Thromb Haemost
. 2003 Aug;
1(8):1838-9.
PMID: 12911602
No abstract available.
8.
Zheng D, MacLean P, Pohnert S, KNIGHT J, Olson A, Winder W, et al.
J Appl Physiol (1985)
. 2001 Aug;
91(3):1073-83.
PMID: 11509501
Skeletal muscle GLUT-4 transcription in response to treatment with 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside (AICAR), a known activator of AMP-activated protein kinase (AMPK), was studied in rats and mice. The increase in GLUT-4 mRNA...
9.
MacLean P, Tanner C, Houmard J, Barakat H
Metabolism
. 2001 Jul;
50(7):783-8.
PMID: 11436182
Plasma cholesteryl ester transfer protein (CETP) activity has been reported to decline during a hyperinsulinemic-euglycemic clamp. It has been suggested that this suppressive effect of acute hyperinsulinemia is linked to...
10.
MacLean P, Zheng D, Dohm G
Exerc Sport Sci Rev
. 2000 Nov;
28(4):148-52.
PMID: 11064847
Among the many effects of exercise is the induction of glucose transporter (GLUT 4) expression in skeletal muscle. In this review, we examine the intracellular signals that may mediate the...