P S Freemont
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Explore the profile of P S Freemont including associated specialties, affiliations and a list of published articles.
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73
Citations
3787
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Recent Articles
1.
Graham N, Junghans C, Downes R, Sendall C, Lai H, McKirdy A, et al.
J Infect
. 2020 Jun;
81(3):411-419.
PMID: 32504743
Objectives: To understand SARS-Co-V-2 infection and transmission in UK nursing homes in order to develop preventive strategies for protecting the frail elderly residents. Methods: An outbreak investigation involving 394 residents...
2.
Rajakumar P, Gowers G, Suckling L, Foster A, Ellis T, Kitney R, et al.
SLAS Technol
. 2018 Sep;
24(3):291-297.
PMID: 30165777
Biofoundries have enabled the ability to automate the construction of genetic constructs using computer-aided design. In this study, we have developed the methodology required to abstract and automate the construction...
3.
Webb A, Kelwick R, Doenhoff M, Kylilis N, MacDonald J, Wen K, et al.
Sci Rep
. 2016 Apr;
6:24725.
PMID: 27090566
Parasitic diseases affect millions of people worldwide, causing debilitating illnesses and death. Rapid and cost-effective approaches to detect parasites are needed, especially in resource-limited settings. A common signature of parasitic...
4.
Dreveny I, Pye V, Beuron F, BRIGGS L, Isaacson R, Matthews S, et al.
Biochem Soc Trans
. 2004 Oct;
32(Pt 5):715-20.
PMID: 15493996
The AAA (ATPase associated with various cellular activities) ATPase, p97, is a hexameric protein of chaperone-like function, which has been reported to interact with a number of proteins of seemingly...
5.
Dokurno P, Lally J, Bates P, Taylor-Papadimitriou J, Band H, Snary D, et al.
Acta Crystallogr D Biol Crystallogr
. 2004 Aug;
53(Pt 6):780-1.
PMID: 15299868
SM3 antibody binds to a tumour-associated epitope on polymorphic epithelial mucin (PEM). Crystals of the Fab fragment of SM3 in complex with a peptide antigen were obtained by vapour diffusion...
6.
Shiels C, Islam S, Vatcheva R, Sasieni P, STERNBERG M, Freemont P, et al.
J Cell Sci
. 2001 Nov;
114(Pt 20):3705-16.
PMID: 11707522
Promyelocytic leukemia (PML) bodies are nuclear multi-protein domains. The observations that viruses transcribe their genomes adjacent to PML bodies and that nascent RNA accumulates at their periphery suggest that PML...
7.
Jensen K, Shiels C, Freemont P
Oncogene
. 2001 Nov;
20(49):7223-33.
PMID: 11704850
PML is a component of a multiprotein complex, termed nuclear bodies, and the PML protein was originally discovered in patients suffering from acute promyelocytic leukaemia (APL). APL is associated with...
8.
Morera S, Lariviere L, Kurzeck J, Freemont P, Janin J, Ruger W
J Mol Biol
. 2001 Aug;
311(3):569-77.
PMID: 11493010
beta-Glucosyltransferase (BGT) is a DNA-modifying enzyme encoded by bacteriophage T4 that transfers glucose from uridine diphosphoglucose to 5-hydroxymethyl cytosine bases of phage T4 DNA. We report six X-ray structures of...
9.
Yuan X, Shaw A, Zhang X, Kondo H, Lally J, Freemont P, et al.
J Mol Biol
. 2001 Aug;
311(2):255-63.
PMID: 11478859
p47 is the major protein identified in complex with the cytosolic AAA ATPase p97. It functions as an essential cofactor of p97-regulated membrane fusion, which has been suggested to disassemble...
10.
Dulic A, Bates P, Zhang X, Martin S, Freemont P, Lindahl T, et al.
Biochemistry
. 2001 May;
40(20):5906-13.
PMID: 11352725
Proteins involved in DNA repair, or its coordination with DNA replication and mitosis through cell cycle checkpoints, are vital in the concerted cellular response to DNA damage that maintains the...