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P S Donnelly

Explore the profile of P S Donnelly including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Grubman A, James S, James J, Duncan C, Volitakis I, Hickey J, et al.
Chem Sci . 2014 Jul; 5(6):2503-2516. PMID: 24976945
Biometals such as zinc, iron, copper and calcium play key roles in diverse physiological processes in the brain, but can be toxic in excess. A hallmark of neurodegeneration is a...
2.
Donnelly P, Harrowfield J, Skelton B, White A
Inorg Chem . 2001 Oct; 40(22):5645-52. PMID: 11599965
Depending upon the position and degree of substitution, carboxymethyl derivatives of cage amines of the "sarcophagine" (3,6,10,13,16,19-hexaazabicyclo[6.6.6]icosane) type vary considerably in the stability of their lactamized forms. For 1,8-diamino-3-carboxymethylsarcophagine, L(1),...
3.
Donnelly P, Harrowfield J, Skelton B, White A
Inorg Chem . 2001 Jan; 39(25):5817-30. PMID: 11151385
Reactions between chloroacetate and both "free" and coordinated forms of the cage amine diaminosarcophagine (1,8-diamino-3,6,10,13,16,19-hexaazabicyclo[6.6.6]icosane) result in the introduction of between one and four pendent carboxymethyl substituents on the nitrogen...