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P Miossec

Explore the profile of P Miossec including associated specialties, affiliations and a list of published articles. Areas
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Articles 177
Citations 2970
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Recent Articles
1.
Miossec P
Bull Acad Natl Med . 2020 Nov; 205(1):43-48. PMID: 33199926
The mechanisms of inflammatory diseases involve the key inflammatory cytokines IL-1, TNF, IL-6, and IL-17 which are now therapeutic targets with biotherapies. They contribute to the local manifestations of clinically...
2.
Robert M, Miossec P
Lupus . 2019 Dec; 29(1):6-14. PMID: 31791181
The involvement of the interleukin (IL)-17 axis in many inflammatory and autoimmune diseases is now well established, and this has led to the development of successful targeted therapies. Its role...
3.
Beringer A, Miossec P
Clin Exp Immunol . 2019 May; 198(1):111-120. PMID: 31102558
Hepatic stellate cells (HSCs) have a central role in liver inflammation and fibrosis by producing inflammatory and fibrotic mediators. Their activation is regulated through direct cell-cell interactions, but also through...
4.
Beringer A, Thiam N, Molle J, Bartosch B, Miossec P
Clin Exp Immunol . 2018 Apr; 193(2):221-233. PMID: 29676779
The proinflammatory cytokines interleukin (IL)-17 and tumour necrosis factor (TNF)-α are targets for treatment in many chronic inflammatory diseases. Here, we examined their role in liver inflammatory response compared to...
5.
Noack M, Ndongo-Thiam N, Miossec P
Clin Exp Immunol . 2016 Jun; 186(1):64-74. PMID: 27328392
In the context of psoriasis, T helper type 17 (Th17) cells infiltrate the inflammatory site and interact with local mesenchymal cells, including skin fibroblasts. The aim of this work was...
6.
Miossec P, Verweij C, Klareskog L, Pitzalis C, Barton A, Lekkerkerker F, et al.
Ann Rheum Dis . 2011 Jul; 70(10):1713-8. PMID: 21784723
Rheumatoid arthritis (RA) is one of the most appropriate conditions for the application of personalised medicine as a high degree of heterogeneity has been recognised, which remains to be explained....
7.
Roman S, Hot A, Fabien N, Cordier J, Miossec P, Ninet J, et al.
Dis Esophagus . 2010 Dec; 24(5):299-304. PMID: 21166734
Esophageal involvement occurs in about 80% of patients with systemic sclerosis, with a marked diminution of peristaltic pressures in the distal two-thirds of the esophagus. Our aims were to more...
8.
Tournadre A, Lenief V, Miossec P
Arthritis Rheum . 2010 Mar; 62(7):2144-51. PMID: 20309865
Objective: To assess the expression of Toll-like receptor 3 (TLR-3) and TLR-7 in muscle tissue from patients with polymyositis (PM) and dermatomyositis (DM) and to investigate the function and regulation...
9.
Appel H, Loddenkemper C, Miossec P
Clin Exp Rheumatol . 2009 Oct; 27(4 Suppl 55):S15-9. PMID: 19822040
Histomorphological analysis of inflammatory lesions in rheumatoid arthritis (RA) and ankylosing spondylitis (AS) display similarities but also major differences. Ankylosing spondylitis is characterised by two key pathological findings: sacroiliac joint...
10.
Reynier F, Verjat T, Turrel F, Imbert P, Marotte H, Mougin B, et al.
Scand J Immunol . 2009 Aug; 70(3):295-9. PMID: 19703019
To study the viral loads of human endogenous retrovirus HERV-K (HML-2) type 1 and type 2 in rheumatoid arthritis (RA), we measured the viral loads of HERV-K (HML-2) type 1...