P Mantuano
Overview
Explore the profile of P Mantuano including associated specialties, affiliations and a list of published articles.
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Snapshot
Snapshot
Articles
3
Citations
25
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
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Published In
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Recent Articles
1.
Sanarica F, Mantuano P, Conte E, Cozzoli A, Capogrosso R, Giustino A, et al.
Pharmacol Res
. 2019 May;
145:104260.
PMID: 31059789
Src tyrosine kinase (TK), a redox-sensitive protein overexpressed in dystrophin-deficient muscles, can contribute to damaging signaling by phosphorylation and degradation of β-dystroglycan (β-DG). We performed a proof-of-concept preclinical study to...
2.
Porcelli L, Quatrale A, Mantuano P, Silvestris N, Rolland J, Biancolillo L, et al.
Curr Pharm Des
. 2012 Sep;
19(5):918-26.
PMID: 22973960
Single-agent therapy with molecularly targeted agents has shown limited success in tumor growth control, mainly because escape or resistance mechanisms are activated once a signalling molecule is inhibited. Rational combinations...
3.
Porcelli L, Quatrale A, Mantuano P, Silvestris N, Brunetti A, Calvert H, et al.
Curr Med Chem
. 2012 Jul;
19(23):3858-73.
PMID: 22788762
A large body of evidence point out that the onset of synthetic lethality may provide a useful tool for amplifying the efficacy of drugs in anticancer regimens, to uncover interdependence...