Alpha 2.0
Login Register
» Authors » P M Tapley

P M Tapley

Explore the profile of P M Tapley including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 6
Citations 74
Followers 0
Related Specialties
Biochemistry
Oncology
Cell Biology
Top 10 Co-Authors
A W Murray
G R Guy
A B Lyons
S C Clark
L B To
L S Park
M Froscio
M J Jones
A F Lopez
J M Eglinton
Published In
Carcinogenesis
Biochem Biophys Res Commun
J Cell Physiol
Eur J Biochem
Affiliations
Soon will be listed here.
Recent Articles
1.
Human interleukin-3 inhibits the binding of granulocyte-macrophage colony-stimulating factor and interleukin-5 to basophils and strongly enhances their functional activity
Lopez A, Eglinton J, Lyons A, Tapley P, To L, Park L, et al.
J Cell Physiol . 1990 Oct; 145(1):69-77. PMID: 1698795
The human T cell-derived cytokines interleukin (IL)-3, granulocyte-macrophage colony-stimulating factor (GM-CSF), and IL-5 were examined for their ability to bind specifically to human basophils and to regulate their function. Scatchard...
2.
Evidence that treatment of platelets with phorbol ester causes proteolytic activation of Ca2+-activated, phospholipid-dependent protein kinase
Tapley P, Murray A
Eur J Biochem . 1985 Sep; 151(2):419-23. PMID: 3161728
Incubation of human platelets with the phorbol ester 12-O-tetradecanoyl-phorbol-13-acetate (TPA) caused the accumulation of a protein kinase in the particulate fraction which was not dependent on Ca2+ and phosphatidylserine (Ptd-Ser)....
3.
Modulation of Ca2+-activated, phospholipid-dependent protein kinase in platelets treated with a tumor-promoting phorbol ester
Tapley P, Murray A
Biochem Biophys Res Commun . 1984 Jul; 122(1):158-64. PMID: 6234894
Incubation of human platelets with 12-0-tetradecanoylphorbol-13-acetate (TPA) caused a rapid decrease in soluble Ca2+, phospholipid-dependent protein kinase activity (protein kinase C) and an increase in protein kinase C associated with...
4.
Platelet Ca2+-activated, phospholipid-dependent protein kinase: evidence for proteolytic activation of the enzyme in cells treated with phospholipase C1
Tapley P, Murray A
Biochem Biophys Res Commun . 1984 Feb; 118(3):835-41. PMID: 6231025
Incubation of human platelets with C. perfringens phospholipase C caused an increase in soluble protein kinase activity assayed in the presence of EGTA, and a decrease in Ca2+/phospholipid-dependent protein kinase...
5.
Resistance of A-431 epidermoid carcinoma cells to early membrane changes induced by tumour promoters
Froscio M, Tapley P, Guy G, Pappalardo S, Jones M, Murray A
Carcinogenesis . 1982 Jan; 3(7):837-9. PMID: 6811153
The A-431 human epidermoid carcinoma cell line was resistant to 12-O-tetradecanoylphorbol-13-acetate (TPA) inhibition of epidermal growth factor binding, enhanced incorporation of [3H]choline into phospholipids and uptake of 86Rb an [3H]2-deoxyglucose....
6.
Tumor promoter inhibition of intercellular communication between cultured mammalian cells
Guy G, Tapley P, Murray A
Carcinogenesis . 1981 Jan; 2(3):223-7. PMID: 7273307
Cocultures were established of a cell line deficient in hypoxanthine-guanine phosphoribosyltransferase (PG-19; HPRT-) and a mouse epidermal cell line (HEL-37; HPRT+). The cocultures were incubated in a medium containing hypoxanthine,...