P Kohonen
Overview
Explore the profile of P Kohonen including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
302
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Recent Articles
1.
Pavet V, Shlyakhtina Y, He T, Ceschin D, Kohonen P, Perala M, et al.
Cell Death Dis
. 2014 Feb;
5:e1043.
PMID: 24481457
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL/TNFSF10/Apo2L) holds promise for cancer therapy as it induces apoptosis in a large variety of cancer cells while exerting negligible toxicity in normal ones. However,...
2.
He T, Haapa-Paananen S, Kaminskyy V, Kohonen P, Fey V, Zhivotovsky B, et al.
Oncogene
. 2013 Sep;
33(27):3538-49.
PMID: 24013224
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is a promising agent in selectively killing tumor cells. However, TRAIL monotherapy has not been successful as many cancer cells are resistant to TRAIL....
3.
Bjorkman M, Ostling P, Harma V, Virtanen J, Mpindi J, Rantala J, et al.
Oncogene
. 2011 Nov;
31(29):3444-56.
PMID: 22120715
Our understanding of key epigenetic regulators involved in specific biological processes and cancers is still incomplete, despite great progress in genome-wide studies of the epigenome. Here, we carried out a...
4.
Harma V, Knuuttila M, Virtanen J, Mirtti T, Kohonen P, Kovanen P, et al.
Oncogene
. 2011 Oct;
31(16):2075-89.
PMID: 21996742
Normal prostate and some malignant prostate cancer (PrCa) cell lines undergo acinar differentiation and form spheroids in three-dimensional (3-D) organotypic culture. Acini formed by PC-3 and PC-3M, less pronounced also...
5.
Haapa-Paananen S, Kiviluoto S, Waltari M, Puputti M, Mpindi J, Kohonen P, et al.
Oncogene
. 2011 Jul;
31(10):1299-310.
PMID: 21785461
Malignant glioma is the most common brain tumor with 16,000 new cases diagnosed annually in the United States. We performed a systematic large-scale transcriptomics data mining study of 9783 tissue...
6.
Leivonen S, Makela R, Ostling P, Kohonen P, Haapa-Paananen S, Kleivi K, et al.
Oncogene
. 2009 Aug;
28(44):3926-36.
PMID: 19684618
Predicting the impact of microRNAs (miRNAs) on target proteins is challenging because of their different regulatory effects at the transcriptional and translational levels. In this study, we applied a novel...
7.
Kohonen P, Nera K, Lassila O
Scand J Immunol
. 2007 Jul;
66(2-3):113-21.
PMID: 17635788
The purpose of this review is to discuss the use of chicken and other model organisms in the study of B-cell development and function as well as to highlight the...
8.
Suonpaa P, Kohonen P, Koskela K, Koskiniemi H, Salminen-Mankonen H, Lassila O
Scand J Immunol
. 2005 Sep;
62(3):218-23.
PMID: 16179008
The first haematopoietic stem cells (HSC) develop in the dorsal aorta as haematopoietic intra-aortic clusters (HIAC). To evaluate the initial steps of definitive haematopoiesis, we have studied the emergence and...
9.
Kohonen P, Nera K, Lassila O
Scand J Immunol
. 2004 Jul;
60(1-2):100-7.
PMID: 15238078
Abstract Helios (Znfn1a2) is an Ikaros-related lymphoid regulatory protein with possible involvement in T-cell development and function as well as in the early events of haematopoietic stem cell differentiation. To...
10.
Koskela K, Nieminen P, Kohonen P, Salminen H, Lassila O
Scand J Immunol
. 2004 May;
59(5):449-57.
PMID: 15140054
Previous studies on mammals have demonstrated that a tumour necrosis factor family member, B-cell-activating factor (BAFF) (BlyS, TALL-1), is mainly produced by myeloid and dendritic cells and that BAFF promotes...