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P J Mullenix

Explore the profile of P J Mullenix including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Waber D, Carpentieri S, Klar N, Silverman L, Schwenn M, Hurwitz C, et al.
J Pediatr Hematol Oncol . 2000 Jun; 22(3):206-13. PMID: 10864051
Purpose: The cognitive sequelae of treatment for childhood acute lymphoblastic leukemia (ALL) were compared in a group of patients who received dexamethasone during the intensification and maintenance phases of therapy...
2.
Mullenix P, Denbesten P, Schunior A, Kernan W
Neurotoxicol Teratol . 1995 Mar; 17(2):169-77. PMID: 7760776
Fluoride (F) is known to affect mineralizing tissues, but effects upon the developing brain have not been previously considered. This study in Sprague-Dawley rats compares behavior, body weight, plasma and...
3.
Schunior A, Mullenix P, Zengel A, Landy H, Howes A, Tarbell N
Pediatr Res . 1994 Apr; 35(4 Pt 1):416-23. PMID: 8047378
CNS therapy for childhood leukemia has adverse effects upon growth and cognition. The cause of these deficits is unknown. In a rat model, we determined which agent, or combination of...
4.
Mullenix P, Kernan W, Schunior A, Howes A, Waber D, Sallan S, et al.
Pediatr Res . 1994 Feb; 35(2):171-8. PMID: 8165051
Children with leukemia receive CNS therapy to improve long-term survival. Neurotoxic effects, such as cognitive impairment, have been associated with this therapy. A rat model was developed to determine which...
5.
Kernan W, Mullenix P
Pharmacol Biochem Behav . 1991 Jul; 39(3):747-54. PMID: 1784603
The computer pattern recognition system for the study of spontaneous rat behavior has allowed new analytical techniques which expand the definition of experimentally induced changes in behavior. As with any...
6.
Mullenix P, Tassinari M, Schunior A, Kernan W
Fundam Appl Toxicol . 1991 Apr; 16(3):495-505. PMID: 1677339
Spontaneous behavior subsequent to acute oral administration of high doses of aspartame, phenylalanine, or tyrosine was analyzed using a computer pattern recognition system. Sprague-Dawley male rats (250-300 g) were dosed...
7.
Norton S, Kimler B, Mullenix P
Neurotoxicol Teratol . 1991 Mar; 13(2):181-8. PMID: 2046638
The deleterious effects of ionizing radiation on the developing brain may be not only prolonged but progressive. Fetuses were exposed to 0.75 Gy of ionizing radiation on gestational day 15...
8.
Mullenix P, Kernan W, Tassinari M, Schunior A, Waber D, Howes A, et al.
Cancer Res . 1990 Oct; 50(20):6461-5. PMID: 2208105
Central nervous system prophylactic therapy used in the treatment of acute lymphoblastic leukemia can reduce intelligence quotient scores and impair memory and attention in children. Cranial irradiation, intrathecal methotrexate, and...
9.
Schunior A, Zengel A, Mullenix P, Tarbell N, Howes A, Tassinari M
Cancer Res . 1990 Oct; 50(20):6455-60. PMID: 2208104
Many long term survivors of childhood acute lymphoblastic leukemia have short stature, as well as craniofacial and dental abnormalities, as side effects of central nervous system prophylactic therapy. An animal...
10.
Kernan Jr W, Mullenix P, Hopper D
Pharmacol Biochem Behav . 1989 Dec; 34(4):863-9. PMID: 2623039
The spontaneous behavior of rats was monitored, classified and analyzed using a recently developed computer pattern recognition system. The K-function, a parameter developed for statistical research on spatial point processes...