P J Gough
Overview
Explore the profile of P J Gough including associated specialties, affiliations and a list of published articles.
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Articles
20
Citations
933
Followers
0
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Recent Articles
1.
Berger S, Bertin J, Gough P
Cell Death Discov
. 2016 Aug;
2:16056.
PMID: 27551544
No abstract available.
2.
Berger S, Harris P, Nagilla R, Kasparcova V, Hoffman S, Swift B, et al.
Cell Death Discov
. 2016 Aug;
1:15009.
PMID: 27551444
Necroptosis and signaling regulated by RIP1 kinase activity is emerging as a key driver of inflammation in a variety of disease settings. A significant amount has been learned about how...
3.
Shutinoski B, Alturki N, Rijal D, Bertin J, Gough P, Schlossmacher M, et al.
Cell Death Differ
. 2016 Jun;
23(10):1628-37.
PMID: 27258786
Receptor interacting protein kinase 1 (RIPK1) participates in several cell signaling complexes that promote cell activation and cell death. Stimulation of RIPK1 in the absence of caspase signaling induces regulated...
4.
Berger S, Bertin J, Gough P
Cell Death Dis
. 2015 Sep;
6:e1889.
PMID: 26379194
No abstract available.
5.
Geserick P, Wang J, Schilling R, Horn S, Harris P, Bertin J, et al.
Cell Death Dis
. 2015 Sep;
6:e1884.
PMID: 26355347
Acquired or intrinsic resistance to apoptotic and necroptotic stimuli is considered a major hindrance of therapeutic success in malignant melanoma. Inhibitor of apoptosis proteins (IAPs) are important regulators of apoptotic...
6.
Preyat N, Rossi M, Kers J, Chen L, Bertin J, Gough P, et al.
Cell Death Differ
. 2015 May;
23(1):29-40.
PMID: 26001219
Cellular necrosis has long been regarded as an incidental and uncontrolled form of cell death. However, a regulated form of cell death termed necroptosis has been identified recently. Necroptosis can...
7.
Moriwaki K, Bertin J, Gough P, Orlowski G, Chan F
Cell Death Dis
. 2015 Feb;
6:e1636.
PMID: 25675296
Apoptosis is a key mechanism for metazoans to eliminate unwanted cells. Resistance to apoptosis is a hallmark of many cancer cells and a major roadblock to traditional chemotherapy. Recent evidence...
8.
Roberts L, Taylor J, Gough P, Forman D, Garcia de Leaniz C
J Fish Biol
. 2014 Dec;
85(6):1972-91.
PMID: 25469954
This study tested the 'silver spoon' hypothesis which posits that individuals that develop under favourable conditions should enjoy a fitness advantage later in life because they are more likely to...
9.
Stringwell R, Lock A, Stutchbury C, Baggett E, Taylor J, Gough P, et al.
J Fish Biol
. 2014 Dec;
85(6):1927-45.
PMID: 25469952
Changes in body shape, fluctuating asymmetry (FA) and crypsis were compared among Atlantic salmon Salmo salar fry kept as controls in captivity and those released and subsequently recaptured in the...
10.
Mattock K, Gough P, Humphries J, Burnand K, Patel L, Suckling K, et al.
Atherosclerosis
. 2009 Aug;
208(1):83-9.
PMID: 19671471
Objective: The cysteine protease, legumain, is thought to have a role in the processing and activation of proteases such as cathepsin-L, which have been implicated in plaque rupture. This study...