P J Dekker
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Explore the profile of P J Dekker including associated specialties, affiliations and a list of published articles.
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27
Citations
697
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Recent Articles
1.
Umapathy N, Dekker P
Arch Otolaryngol Head Neck Surg
. 2003 Oct;
129(10):1053-5.
PMID: 14568786
Objective: To evaluate the results of myringoplasty in children 4 to 14 years old at the time of surgery. Design: Retrospective analysis of case notes for 100 consecutive children who...
2.
van Wilpe S, Ryan M, Hill K, Maarse A, Meisinger C, Brix J, et al.
Nature
. 1999 Oct;
401(6752):485-9.
PMID: 10519552
Mitochondrial preproteins are imported by a multisubunit translocase of the outer membrane (TOM), including receptor proteins and a general import pore. The central receptor Tom22 binds preproteins through both its...
3.
Rassow J, Dekker P, van Wilpe S, Meijer M, Soll J
J Mol Biol
. 1999 Feb;
286(1):105-20.
PMID: 9931253
Growing mitochondria acquire most of their proteins by the uptake of mitochondrial preproteins from the cytosol. To mediate this protein import, both mitochondrial membranes contain independent protein transport systems: the...
4.
Dekker P, Ryan M, Brix J, Muller H, Honlinger A, Pfanner N
Mol Cell Biol
. 1998 Oct;
18(11):6515-24.
PMID: 9774667
The preprotein translocase of the outer mitochondrial membrane (Tom) is a multisubunit machinery containing receptors and a general import pore (GIP). We have analyzed the molecular architecture of the Tom...
5.
Palmisano A, Zara V, Honlinger A, Vozza A, Dekker P, Pfanner N, et al.
Biochem J
. 1998 Jun;
333 ( Pt 1):151-8.
PMID: 9639574
We have studied the targeting and assembly of the 2-oxoglutarate carrier (OGC), an integral inner-membrane protein of mitochondria. The precursor of OGC, synthesized without a cleavable presequence, is transported into...
6.
Dekker P, Martin F, Maarse A, Bomer U, Muller H, Guiard B, et al.
EMBO J
. 1997 Oct;
16(17):5408-19.
PMID: 9312000
Preprotein import into mitochondria is mediated by translocases located in the outer and inner membranes (Tom and Tim) and a matrix Hsp70-Tim44 driving system. By blue native electrophoresis, we identify...
7.
Dekker P, Pfanner N
J Mol Biol
. 1997 Jul;
270(3):321-7.
PMID: 9237899
The yeast mitochondrial GrpE homologue, Mge1, assists matrix Hsp70 in both protein translocation across the mitochondrial membranes and subsequent protein folding. We expressed mtHsp70 and Mge1 in Escherichia coli and...
8.
Dietmeier K, Honlinger A, Bomer U, Dekker P, Eckerskorn C, Lottspeich F, et al.
Nature
. 1997 Jul;
388(6638):195-200.
PMID: 9217162
Most mitochondrial proteins are synthesized as preproteins on cytosolic polysomes and are subsequently imported into the organelle. The mitochondrial outer membrane contains a multisubunit preprotein translocase (Tom) which has receptors...
9.
Bomer U, Meijer M, Maarse A, Honlinger A, Dekker P, Pfanner N, et al.
EMBO J
. 1997 May;
16(9):2205-16.
PMID: 9171336
The protein transport machinery of the inner mitochondrial membrane contains three essential Tim proteins. Tim17 and Tim23 are thought to build a preprotein translocation channel, while Tim44 transiently interacts with...
10.
Dekker P, Muller H, Rassow J, Pfanner N
Biol Chem
. 1996 Jul;
377(7-8):535-8.
PMID: 8922289
The mitochondrial outer membrane contains import receptors for nuclear-encoded preproteins and a general import pore responsible for membrane translocation of preproteins. Receptors and the general import pore have been suggested...