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P H Basse

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Citations 290
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Recent Articles
1.
Albertsson P, Basse P, Edsparr K, Kim M, Goldfarb R, Golfarb R, et al.
Scand J Immunol . 2007 Sep; 66(4):402-9. PMID: 17850584
Tumour infiltration by activated natural killer (A-NK) cells is a pre-requisite for tumour eradication by adoptive NK cell transfer. Extravasated A-NK cells do not always succeed in reaching the crucial...
2.
Yang Q, Goding S, Hokland M, Basse P
Immunol Res . 2007 Mar; 36(1-3):13-25. PMID: 17337762
NK cells have been shown to play an important role in the lungs with regards to tumor cell clearance and resistance of this organ to metastases. Here, we have investigated...
3.
Goding S, Yang Q, Mi Z, Robbins P, Basse P
Cancer Gene Ther . 2007 Feb; 14(5):441-50. PMID: 17273184
Despite successes in animals, cytokine gene expression selectively in human tumors is difficult to achieve owing to lack of efficient delivery methods. Since interleukin (IL)-2-activated natural killer (A-NK) and phytohemagglutinin...
4.
Yang Q, Goding S, Hagenaars M, Carlos T, Albertsson P, Kuppen P, et al.
Cancer Immunol Immunother . 2005 Jul; 55(6):699-707. PMID: 16047144
We have recently shown that adoptively transferred, IL-2-activated natural killer (A-NK) cells are able to eliminate well-established B16-F10.P1 melanoma lung metastases. However, some B16-F10.P1 lung metastases were resistant to infiltration...
5.
Sandel M, Speetjens F, Menon A, Albertsson P, Basse P, Hokland M, et al.
Mol Immunol . 2004 Dec; 42(4):541-6. PMID: 15607811
A majority of colorectal adenocarcinomas displays diminished MHC class I expression, making them particularly vulnerable for NK cell-mediated killing. Generally, these tumors also show a substantial inflammatory infiltrate. Most inflammatory...
6.
Basse P, Whiteside T, Chambers W, Herberman R
Int Rev Immunol . 2002 Mar; 20(3-4):439-501. PMID: 11878512
While it is generally accepted that natural killer (NK) cells, by killing tumor cells in the circulation, represent a first line of defense against metastases, their therapeutic activity against established...
7.
Hagenaars M, Ensink N, Basse P, Hokland M, Nannmark U, Eggermont A, et al.
Clin Exp Metastasis . 2001 Mar; 18(2):189-96. PMID: 11235995
The colon adenocarcinoma cell line CC531 was adopted as a model for immunotherapeutical treatment of experimental colorectal metastases in a syngeneic rat model. We studied the presence and localization of...
8.
Kuppen P, van der Eb M, Jonges L, Hagenaars M, Hokland M, Nannmark U, et al.
Histochem Cell Biol . 2001 Feb; 115(1):67-72. PMID: 11219610
In this article we report about the role that tumor structure and extracellular matrix (ECM) may play in immunotherapy and in gene therapy using adenoviruses. We performed studies in a...
9.
Nannmark U, Hokland M, Agger R, Christiansen M, Kjaergaard J, Goldfarb R, et al.
In Vivo . 2000 Dec; 14(5):651-8. PMID: 11125549
The circulatory pattern of IL-2 activated natural killer (A-NK) cells was studied in C57BL/6 mice bearing 10 day-old pulmonary and subcutaneous (s.c.) metastases of the B16 melanoma in order to...
10.
Bergman I, Basse P, Barmada M, Griffin J, Cheung N
Cancer Immunol Immunother . 2000 Aug; 49(4-5):259-66. PMID: 10941909
Antibodies can direct tumor cell lysis by activating complement-mediated and cell-mediated cytoxicities (antibody-dependent cell-mediated cytotoxicity, ADCC). Clinical translation of these effects into successful cancer therapy has been slow. Choosing an...