P E Squires
Overview
Explore the profile of P E Squires including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
42
Citations
483
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0
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Recent Articles
1.
Cliff C, Squires P, Hills C
Cell Commun Signal
. 2024 Jul;
22(1):351.
PMID: 38970061
Background: Accompanied by activation of the NOD-like receptor protein 3 (NLRP3) inflammasome, aberrant connexin 43 (Cx43) hemichannel-mediated ATP release is situated upstream of inflammasome assembly and inflammation and contributes to...
2.
Williams B, Cliff C, Lee K, Squires P, Hills C
Front Physiol
. 2022 Jun;
13:907504.
PMID: 35755447
The NOD-like receptor protein 3 (NLRP3) inflammasome is a multi-protein signalling complex integral to the chronic inflammatory response, activated in response to sterile and non-sterile cellular damage. The assembly and...
3.
Hills C, Siamantouras E, Smith S, Cockwell P, Liu K, Squires P
Diabetologia
. 2012 Jan;
55(3):812-24.
PMID: 22215279
Aims/hypothesis: A key pathology in diabetic nephropathy is tubulointerstitial fibrosis. The condition is characterised by increased deposition of the extracellular matrix, fibrotic scar formation and declining renal function, with the...
4.
Hodgkin M, Hills C, Squires P
J Endocrinol
. 2008 Jun;
199(1):1-4.
PMID: 18573921
In the 15 years since the identification and characterisation of the extracellular calcium-sensing receptor (CaR), it has become increasingly apparent that this cationic binding receptor is found in many tissues,...
5.
Persaud S, Jones P, Roderigo-Milne H, Buchan A, Squires P
Biochem Biophys Res Commun
. 2003 Feb;
300(4):889-93.
PMID: 12559956
Cytosolic phospholipase A(2)(cPLA(2)), an enzyme responsible for the generation of arachidonic acid, is located in the cytosolic compartment in most tissues and it translocates to membrane compartments when activated. We...
6.
Squires P, Persaud S, Hauge-Evans A, Gray E, Ratcliff H, Jones P
Cell Calcium
. 2002 Jul;
31(5):209-19.
PMID: 12098223
Isolated beta-cells are heterogeneous in sensory, biosynthetic and secretory capabilities, however, to enable efficient and appropriate secretion, cellular activity within the intact islet is synchronised. Historically, the entrainment of activity...
7.
Hauge-Evans A, Squires P, Belin V, Ramracheya R, Persaud S, Jones P
Mol Cell Endocrinol
. 2002 Jun;
191(2):167-76.
PMID: 12062900
Insulin secretion from MIN6 cells configured as cell aggregates by culture on a gelatin substrate (pseudoislets) is enhanced compared to that of MIN6 cells grown as monolayers on tissue culture...
8.
Whitehouse B, Gyles S, Squires P, Sayed S, Burns C, Persaud S, et al.
J Endocrinol
. 2002 Mar;
172(3):583-93.
PMID: 11874707
Y1 adrenocortical cells respond to activators of the cyclic AMP-dependent protein kinase (PKA) signalling pathway not only with increases in steroid secretion but also with a characteristic change in cell...
9.
10.
Harris T, Squires P, Michael A, Bernal A, Abayasekara D
Biochem Biophys Res Commun
. 2001 Aug;
285(5):1089-94.
PMID: 11478765
Prostaglandin E(2) (PGE(2)) exerts mainly luteotrophic effects in the corpus luteum. In other tissues, PGE(2) acts via specific PGE(2) receptor subtypes including EP1, which modulates intracellular calcium ([Ca(2+)](i)) and EP2,...