P Charles Lin
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Explore the profile of P Charles Lin including associated specialties, affiliations and a list of published articles.
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45
Citations
2315
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Recent Articles
1.
Qu P, Wuest T, Min Y, Alevizos I, Young H, Lin P
J Autoimmun
. 2020 Oct;
116:102559.
PMID: 33087256
Autoimmune disorders are the third most common diseases in the United States, and affect the daily lives of millions of people. In this study, we analyzed patient samples, utilized a...
2.
Hong J, Min Y, Wuest T, Lin P
Cancers (Basel)
. 2020 May;
12(6).
PMID: 32471123
The vascular response to hypoxia and ischemia is essential for maintaining homeostasis during stressful conditions and is particularly critical for vital organs such as the heart. Hypoxia-inducible factor-1 (HIF-1) is...
3.
Hong J, Kim Y, Yanpallewar S, Lin P
Int J Mol Sci
. 2020 Feb;
21(4).
PMID: 32079227
Vav1 is a Rho/Rac (Ras-related C3 botulinum toxin substrate) guanine nucleotide exchange factor expressed in hematopoietic and endothelial cells that are involved in a wide range of cellular functions. It...
4.
Hong J, Qu P, Wuest T, Huang H, Huang C, Lin P
Immune Netw
. 2019 Nov;
19(5):e34.
PMID: 31720045
Neutrophilic granule protein (NGP) was previously reported as a granular protein of neutrophils in mouse, but the function has not been known clearly. We found the presence of the possible...
5.
Hong J, Wuest T, Min Y, Lin P
Cancers (Basel)
. 2019 Nov;
11(11).
PMID: 31717697
Oxygen sensing is crucial for adaptation to variable habitats and physiological conditions. Low oxygen tension, or hypoxia, is a common feature of solid tumors, and hypoxic tumors are often more...
6.
Hong J, Kim S, Lin P
J Interferon Cytokine Res
. 2018 Sep;
39(1):61-71.
PMID: 30256696
Interleukin-33 (IL-33) is one of the members of the IL-1 family of cytokines and a ligand of ST2 and IL-1 receptor accessory protein (IL-1RAcP) that is known to affect Th2...
7.
Mackert J, Qu P, Min Y, Johnson P, Yang L, Lin P
Sci Rep
. 2017 Oct;
7(1):14048.
PMID: 29070836
Myeloid-derived suppressor cells (MDSCs) are greatly expanded in cancer patients and tumor-bearing mice. They infiltrate into tumors and modulate the tumor microenvironment. In an effort to identify molecular mediators responsible...
8.
Hollander M, Latour L, Yang D, Ishii H, Xiao Z, Min Y, et al.
Circ Res
. 2017 Oct;
121(12):1360-1369.
PMID: 29051340
Rationale: Cryptogenic strokes, those of unknown cause, have been estimated as high as 30% to 40% of strokes. Inflammation has been suggested as a critical etiologic factor. However, there is...
9.
Min Y, Li J, Qu P, Lin P
Oncotarget
. 2017 Sep;
8(31):50582-50593.
PMID: 28881585
Vascular endothelial cells and Gr-1+CD11b+ myeloid derived suppressor cells (MDSCs) are two important components that constitute the tumor microenvironment. Targeting these cells offers the potential to halt tumor growth. In...
10.
Yang L, Lin P
Semin Cancer Biol
. 2017 Aug;
47:185-195.
PMID: 28782608
Treatment of cancer metastasis has been largely ineffective. It is paramount to understand the mechanisms underlying the metastatic process, of which the tumor microenvironment is an indispensable participant. What are...