P C Kothary
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Explore the profile of P C Kothary including associated specialties, affiliations and a list of published articles.
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Articles
22
Citations
38
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Recent Articles
1.
Hashimoto M, Kothary P, Raper S
J Surg Res
. 1999 Feb;
81(2):164-9.
PMID: 9927535
Background: The simultaneous administration of carbon tetrachloride (CCl4) and phenobarbital in the rat produces one of the most common experimental models of liver cirrhosis. As phenobarbital also has a hepatotrophic...
2.
Hashimoto M, Kothary P, Eckhauser F, Raper S
J Gastroenterol Hepatol
. 1999 Jan;
13(12):1259-65.
PMID: 9918436
Prevention of postoperative hepatic failure is important after hepatic resection. In patients with cirrhosis, impaired liver function and regenerative capacity after major hepatic resection are associated with increased morbidity and...
3.
Kusaka K, Kothary P, Del Monte M
Curr Eye Res
. 1998 Jun;
17(5):524-30.
PMID: 9617548
Purpose: We investigated the effect of retinoic acid (RA) on basic fibroblast growth factor (bFGF)-stimulated proliferation of cultured human retinal pigment epithelial (hRPE) cells and of 125I-bFGF-binding to the bFGF...
4.
Bitar K, Kothary S, Kothary P
J Pharmacol Exp Ther
. 1996 Feb;
276(2):714-9.
PMID: 8632341
The effect of somatostatin on Bombesin-induced contraction of isolated rabbit colonic smooth muscle cells was examined. Preincubation of muscle cells with somatostatin 10(-6) M inhibited bombesin-induced contraction. To characterize somatostatin...
5.
Kothary P, Kokudo N, Eckhauser F, Delvalle J, Raper S
J Cell Biochem
. 1995 Oct;
59(2):258-65.
PMID: 8904319
The role of somatostatin (SS-14) in the regulation of rat liver regeneration was examined by using thymidine incorporation into hepatocyte DNA labeled with tritiated thymidine, a nuclear-labeling index, and the...
6.
Imanishi H, Kothary P, Bhora F, Eckhauser F, Raper S
J Surg Res
. 1995 Apr;
58(4):435-40.
PMID: 7723325
Cirrhotic livers are considered to regenerate less actively than normal livers after hepatic resection. Little is known about the mechanisms responsible for impaired capacity of regeneration in cirrhotic liver. In...
7.
Bhora F, Kothary P, Imanishi H, Eckhauser F, Raper S
J Surg Res
. 1994 Dec;
57(6):706-10.
PMID: 7996850
Liver regeneration following partial hepatectomy is significantly impaired in rats with hereditary vasopressin (AVP) deficiency. This suggested that AVP might have a direct effect on cultured rat hepatocytes. Hepatocytes from...
8.
McLeod M, Kothary P, Farrell C
J Surg Res
. 1994 Nov;
57(5):619-24.
PMID: 7526047
Inhibitory G proteins (Gi) play an important role in cell proliferation. In order to characterize Gi proteins in RINm5F (RIN) cells, we first established RIN cells in cell culture. Immunoblot...
9.
Hashimoto M, Kothary P, Raper S
Regul Pept
. 1993 Mar;
44(1):49-59.
PMID: 8097889
Transforming growth factor alpha (TGF alpha) stimulates DNA synthesis in adult rat hepatocytes, and plays a physiological role after partial hepatectomy by an autocrine mechanism. Somatostatin (SS-14) is a potent...
10.
Raper S, Kothary P, Kokudo N, Delvalle J
Am J Surg
. 1993 Jan;
165(1):89-94; discussion 94-5.
PMID: 8093425
Somatostatin-14 (SS-14) inhibits the hepatotrophic effect of a variety of growth factors in cultured hepatocytes. We hypothesized that hepatic somatostatin processing might be altered during regeneration. Male Sprague-Dawley rats underwent...