P C Bridgman
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Explore the profile of P C Bridgman including associated specialties, affiliations and a list of published articles.
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34
Citations
1011
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Recent Articles
1.
Kollins K, Hu J, Bridgman P, Huang Y, Gallo G
Dev Neurobiol
. 2009 Feb;
69(5):279-98.
PMID: 19224562
The earliest stage in the development of neuronal polarity is characterized by extension of undifferentiated "minor processes" (MPs), which subsequently differentiate into the axon and dendrites. We investigated the role...
2.
Bridgman P, Dave S, Asnes C, Tullio A, Adelstein R
J Neurosci
. 2001 Aug;
21(16):6159-69.
PMID: 11487639
Growth cones are required for the forward advancement and navigation of growing axons. Modulation of growth cone shape and reorientation of the neurite are responsible for the change of outgrowth...
3.
Bridgman P, Elkin L
J Neurocytol
. 2001 Jul;
29(11-12):831-41.
PMID: 11466474
The myosin super family is an extended family of actin-based motor proteins that can be divided into 15-18 structurally distinct classes (Sellers, J. R (2000) Biochemica et Biophysica Acta, 1496,...
4.
Tullio A, Bridgman P, Tresser N, Chan C, Conti M, Adelstein R, et al.
J Comp Neurol
. 2001 Apr;
433(1):62-74.
PMID: 11283949
Ablation of nonmuscle myosin heavy chain II-B (NMHC-B) in mice results in severe hydrocephalus with enlargement of the lateral and third ventricles. All B(-)/B(-) mice died either during embryonic development...
5.
Bridgman P
J Cell Biol
. 1999 Sep;
146(5):1045-60.
PMID: 10477758
To investigate the role that myosin Va plays in axonal transport of organelles, myosin Va-associated organelle movements were monitored in living neurons using microinjected fluorescently labeled antibodies to myosin Va...
6.
Rochlin M, DAILEY M, Bridgman P
Mol Biol Cell
. 1999 Jul;
10(7):2309-27.
PMID: 10397767
We identify an actin-based protrusive structure in growth cones termed "intrapodium." Unlike filopodia, intrapodia are initiated exclusively within lamellipodia and elongate in a continuous (nonsaltatory) manner parallel to the plane...
7.
Schafer D, Welch M, Machesky L, Bridgman P, Meyer S, Cooper J
J Cell Biol
. 1998 Dec;
143(7):1919-30.
PMID: 9864364
Actin filament assembly is critical for eukaryotic cell motility. Arp2/3 complex and capping protein (CP) regulate actin assembly in vitro. To understand how these proteins regulate the dynamics of actin...
8.
Evans L, Lee A, Bridgman P, Mooseker M
J Cell Sci
. 1998 Jul;
111 ( Pt 14):2055-66.
PMID: 9645952
Myosin-V has been linked to actin-based organelle transport by a variety of genetic, biochemical and localization studies. However, it has yet to be determined whether myosin-V functions as an organelle...
9.
Evans L, Hammer J, Bridgman P
J Cell Sci
. 1997 Feb;
110 ( Pt 4):439-49.
PMID: 9067596
Myosin V-null mice (dilute-lethal mutants) exhibit apparent neurological defects that worsen from birth until death in the third postnatal week. Although myosin V is enriched in brain, the neuronal function...
10.
Rochlin M, Wickline K, Bridgman P
J Neurosci
. 1996 May;
16(10):3236-46.
PMID: 8627361
Microtubules are a primary cytoskeletal constituent of axons and growth cones. In addition to serving as a scaffolding for axon assembly, they also provide a means of transport of organelles...