P A Pierce
Overview
Explore the profile of P A Pierce including associated specialties, affiliations and a list of published articles.
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Articles
21
Citations
239
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Recent Articles
1.
Pierce P, Xie G, Meuser T, Peroutka S
Neuroscience
. 1997 Oct;
81(3):813-9.
PMID: 9316030
Although serotonin has been shown to play an important role in peripheral pain mechanisms, the specific subtypes of serotonin receptors involved in pain and hyperalgesia remain poorly understood. To date,...
2.
Boothe D, Brown S, Fate G, Pierce P, Hanson B, Boothe H, et al.
J Vet Pharmacol Ther
. 1996 Dec;
19(6):491-4.
PMID: 8971680
No abstract available.
3.
Pierce P, Xie G, Peroutka S, Levine J
Reg Anesth
. 1996 May;
21(3):219-25.
PMID: 8744664
Background And Objectives: Sumatriptan is a novel drug for migraine headache pain, which, on the basis of its mechanism of action, may have therapeutic potential in other pain states. Sumatriptan...
4.
Callister R, Donnelly R, Pierce P, Stuart D
J Morphol
. 1996 Feb;
227(2):171-83.
PMID: 8568906
The spinal cord of the adult turtle, Pseudemys (Trachemys) scripta elegans, is now considered a promising model for the study of the segmental motor system in the generalized tetrapod. To...
5.
Pierce P, Xie G, Levine J, Peroutka S
Neuroscience
. 1996 Jan;
70(2):553-9.
PMID: 8848158
While serotonin has been shown to play an important role in peripheral pain mechanisms, the specific subtypes of receptors involved and their differential distribution between the sensory and sympathetic nervous...
6.
Pierce P, Xie G, Peroutka S, Green P, Levine J
J Pharmacol Exp Ther
. 1995 Oct;
275(1):502-8.
PMID: 7562592
5-Hydroxytryptamine (5-HT) is known to act in peripheral tissues to produce pain and inflammation, yet the mechanisms underlying 5-HT-induced inflammation have not been well studied. The present study uses a...
7.
Pierce P, King B, Rampil I, Levine J
Anesthesiology
. 1995 Sep;
83(3):568-73.
PMID: 7661358
Background: In vitro studies demonstrate that halothane, but not isoflurane, inhibits bradykinin-induced calcium currents and prostacyclin release in cultured endothelial cells. Because bradykinin is an important endogenous mediator of inflammation,...
8.
Hagen J, Pierce P, Peroutka S
Biol Signals
. 1994 Sep;
3(5):223-9.
PMID: 7704103
Eleven ergot compounds were competed against [3H]-ketanserin-labelled 5-HT2 receptors in rat and human cortex. Four of the ergots are selective for rat 5-HT2 receptors--mesulergine, methysergide, nicergoline and metergoline, whereas pergolide,...
9.
Pierce P, Kim J, Peroutka S
Naunyn Schmiedebergs Arch Pharmacol
. 1992 Jul;
346(1):4-11.
PMID: 1407003
A molecular structural criterion of ligand selectivity for the 5-HT2 versus 5-HT1C receptor was hypothesized on the basis of radioligand binding data. Despite the large number of compounds which have...
10.
Deliganis A, Pierce P, Peroutka S
Biochem Pharmacol
. 1991 Jun;
41(11):1739-44.
PMID: 1828347
The interactions of the indolealkylamine N,N-dimethyltryptamine (DMT) with 5-hydroxytryptamine1A (5-HT1A) and 5-HT2 receptors in rat brain were analyzed using radioligand binding techniques and biochemical functional assays. The affinity of DMT...