P A McCombe
Overview
Explore the profile of P A McCombe including associated specialties, affiliations and a list of published articles.
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74
Citations
1478
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Recent Articles
1.
Nona R, Greer J, Henderson R, McCombe P
Amyotroph Lateral Scler Frontotemporal Degener
. 2022 May;
24(1-2):24-32.
PMID: 35616250
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease associated with loss of upper and lower motor neurones. It leads to death by respiratory failure and has a typical prognosis of...
2.
Lee A, Klinkradt S, McCombe P, Pow D
Neurosci Lett
. 2022 Apr;
780:136637.
PMID: 35439550
Glutamate transporter 1 is the principal transporter that mediates glutamate clearance in the mammalian brain. In rodents, it is referred to as GLT-1, whereas in humans it is referred to...
3.
Mcgill R, Steyn F, Ngo S, Thorpe K, Heggie S, Henderson R, et al.
Amyotroph Lateral Scler Frontotemporal Degener
. 2021 Aug;
23(5-6):430-437.
PMID: 34396845
To investigate changes in immune markers and frequencies throughout disease progression in patients with amyotrophic lateral sclerosis (ALS). : In this longitudinal study, serial blood samples were collected from 21...
4.
McCombe P, Wray N, Henderson R
Expert Rev Neurother
. 2016 Dec;
17(6):561-577.
PMID: 27983884
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease defined by the presence of muscle weakness. The motor features of disease are heterogeneous in site of onset and progression. There are...
5.
Ioannides Z, Henderson R, Robertson T, Davis M, McCombe P
J Neurol Neurosurg Psychiatry
. 2015 Sep;
87(9):1031-2.
PMID: 26341325
No abstract available.
6.
Ngo S, Steyn F, Huang L, Mantovani S, Pfluger C, Woodruff T, et al.
J Neurol Sci
. 2015 Jul;
357(1-2):22-7.
PMID: 26198021
Amyotrophic lateral sclerosis (ALS) is an adult-onset neurodegenerative disease characterized by the loss of upper cortical and lower motor neurons. ALS causes death within 2-5years of diagnosis. Diet and body...
7.
McCombe P, Pfluger C, Singh P, Lim C, Airey C, Henderson R
J Neurol Sci
. 2015 May;
353(1-2):122-9.
PMID: 25958264
There is a need for a blood biomarker of disease activity in ALS. This marker needs to measure the loss of motor neurones. Phosphorylated neurofilament heavy chain (pNfH) in the...
8.
9.
Mantovani S, Gordon R, Macmaw J, Pfluger C, Henderson R, Noakes P, et al.
J Neuroimmunol
. 2014 Sep;
276(1-2):213-8.
PMID: 25262158
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease, characterized by the progressive loss of motor neurons within the central nervous system. Neural degeneration and inflammatory processes, including activation of...
10.
Ngo S, Steyn F, McCombe P
Front Neuroendocrinol
. 2014 May;
35(3):347-69.
PMID: 24793874
Autoimmune diseases are a range of diseases in which the immune response to self-antigens results in damage or dysfunction of tissues. Autoimmune diseases can be systemic or can affect specific...