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P A Knight

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Recent Articles
1.
Rychter J, Van Nassauw L, Brown J, Marck E, Knight P, Miller H, et al.
Parasite Immunol . 2010 Apr; 32(4):221-31. PMID: 20398222
Deposition of Schistosoma mansoni eggs in the intestinal mucosa is associated with recruitment of mucosal mast cells (MMC) expressing mouse mast cell protease-1 (mMCP-1). We investigated the involvement of mMCP-1...
2.
Knight P, Brown J, Pemberton A
Parasitology . 2008 Apr; 135(6):655-70. PMID: 18413001
SUMMARYGastrointestinal infection with the nematode Trichinella spiralis is accompanied by a rapid and reversible expansion of the mucosal mast cell and goblet cell populations in the intestinal epithelium, which is...
3.
Craig N, Miller H, SMITH W, Knight P
Vet Immunol Immunopathol . 2007 Aug; 120(1-2):47-54. PMID: 17714792
Infection of sheep with Teladorsagia circumcincta triggers an immune response with predominantly type-2 (Th2) characteristics, including local eosinophila, mastocytosis and increased mucus production. In order to better understand the protective...
4.
Knight P, Pate J, SMITH W, Miller H
Vet Immunol Immunopathol . 2007 Aug; 120(1-2):55-60. PMID: 17709146
Mammalian chitinases and chitinase-like proteins are a group of molecules known to be upregulated and secreted in Th2-induced inflammatory responses, such as asthma, allergy and nematode infection. As part of...
5.
Pemberton A, Brown J, Wright S, Knight P, McPHEE M, McEUEN A, et al.
Clin Exp Allergy . 2003 Jul; 33(7):1005-12. PMID: 12859460
Background: Gastrointestinal nematode infection is associated with mucosal mast cell (MMC) hyperplasia. In the mouse, this is accompanied by the release of substantial quantities of the chymase mouse mast cell...
6.
Brown J, Knight P, Wright S, Thornton E, Miller H
Clin Exp Allergy . 2003 Jan; 33(1):132-46. PMID: 12534561
Background: The mucosal mast cell (MMC) granule-specific beta-chymase, mouse mast cell protease-1 (mMCP-1), is released systemically into the bloodstream early in nematode infection before parasite-specific IgE responses develop and TGF-beta1...
7.
Nuttall T, Knight P, McAleese S, Lamb J, Hill P
Vet Immunol Immunopathol . 2002 Jun; 87(3-4):379-84. PMID: 12072261
Atopic dermatitis is a common inflammatory skin disease of humans and dogs. Human atopic dermatitis is associated with T-helper (Th) 2 type responses, although Th1 cytokines are present in chronic...
8.
Nuttall T, Knight P, McAleese S, Lamb J, Hill P
Clin Exp Allergy . 2002 May; 32(5):789-95. PMID: 11994107
Background: Atopic dermatitis is a common inflammatory skin disease of humans and dogs. Human atopic dermatitis is associated with Th2-type responses, although Th1 cytokines can be identified in chronic lesions....
9.
Wright S, Brown J, Knight P, Thornton E, Kilshaw P, Miller H
Clin Exp Allergy . 2002 Apr; 32(2):315-24. PMID: 11929499
Background: Mucosal mast cells (MMC) play a central role in gut hypersensitivities and inflammation. They are morphologically, biochemically and functionally distinct from their connective tissue counterparts. Massive hyperplasia of MMC...
10.
Sumer H, Knight P
J Appl Psychol . 2001 Aug; 86(4):653-63. PMID: 11519649
This study explored whether different models of work-family relationship were possible for individuals with different attachment styles. A mail survey was conducted using employees (N = 481) at a midwestern...