Otoya Sekine
Overview
Explore the profile of Otoya Sekine including associated specialties, affiliations and a list of published articles.
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Articles
12
Citations
38
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Recent Articles
1.
Soma Y, Tohyama S, Kubo A, Yamasaki T, Kabasawa N, Haga K, et al.
iScience
. 2024 Nov;
27(11):111234.
PMID: 39569381
Cardiac regenerative therapy using human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) has been applied in clinical settings. Herein, we aimed to investigate the metabolic profiles of hiPSC-CM grafts. RNA sequencing...
2.
Kobayashi H, Tohyama S, Ichimura H, Ohashi N, Chino S, Soma Y, et al.
Circulation
. 2024 Apr;
150(8):611-621.
PMID: 38666382
Background: The clinical application of human induced pluripotent stem cell-derived cardiomyocytes (CMs) for cardiac repair commenced with the epicardial delivery of engineered cardiac tissue; however, the feasibility of the direct...
3.
Miyama H, Ikemura N, Kimura T, Katsumata Y, Yamashita S, Yamaoka K, et al.
Heart Rhythm
. 2024 Apr;
21(9):1469-1476.
PMID: 38599472
Background: Various treatment approaches for atrial fibrillation (AF) have demonstrated improved health status, yet the significance of these therapeutic interventions in individual patients remains unclear. Objective: This study aimed to...
4.
Miyama H, Himeno Y, Yano S, Yamashita S, Yamaoka K, Ibe S, et al.
Heart Rhythm O2
. 2024 Mar;
5(2):97-102.
PMID: 38545320
Background: The complexity of leadless pacemaker (LP) implantation varies widely. However, the predictive factors determining this difficulty are poorly understood. Objective: The purpose of this study was to evaluate the...
5.
Moriwaki T, Tani H, Haga K, Morita-Umei Y, Soma Y, Umei T, et al.
Cell Rep Methods
. 2023 Dec;
3(12):100666.
PMID: 38113855
Three-dimensional (3D) cultures are known to more closely mimic in vivo conditions compared with 2D cultures. Cardiac spheroids (CSs) and organoids (COs) are useful for 3D tissue engineering and are...
6.
Sekine O, Kanaami S, Masumoto K, Aihara Y, Morita-Umei Y, Tani H, et al.
Stem Cell Reports
. 2023 Sep;
18(10):1925-1939.
PMID: 37738969
Monitoring cardiac differentiation and maturation from human pluripotent stem cells (hPSCs) and detecting residual undifferentiated hPSCs are indispensable for the development of cardiac regenerative therapy. MicroRNA (miRNA) is secreted from...
7.
Tani H, Kobayashi E, Yagi S, Tanaka K, Kameda-Haga K, Shibata S, et al.
Biomaterials
. 2023 Jun;
299:122174.
PMID: 37285642
Although the extracellular matrix (ECM) plays essential roles in heart tissue engineering, the optimal ECM components for heart tissue organization have not previously been elucidated. Here, we focused on the...
8.
Sekine O, Kitakata H, Kohsaka S, Fujisawa D, Nakano N, Shiraishi Y, et al.
Heart Vessels
. 2023 Jun;
38(10):1244-1255.
PMID: 37264250
Shared decision-making (SDM) is a pivotal process in seeking optimal individual treatment and incorporating clinical evidence and patients' autonomous preferences. However, patients' actual attitudes toward participation in decision-making for state-of-the-art...
9.
Kitakata H, Kohno T, Kohsaka S, Fujisawa D, Nakano N, Sekine O, et al.
J Am Heart Assoc
. 2022 Oct;
11(21):e026645.
PMID: 36300657
Background The implementation of advance care planning (ACP) in heart failure management is insufficient. Social isolation (SI) could be a barrier to ACP initiation, albeit the relationship between SI and...
10.
Hashimoto S, Kitakata H, Kohsaka S, Fujisawa D, Shiraishi Y, Nakano N, et al.
J Cardiol
. 2022 Oct;
81(1):42-48.
PMID: 36241046
Background: Understanding patient perspectives of self-care is critical for improving multidisciplinary education programs and adherence to such programs. However, perspectives of self-care for patients with heart failure (HF) as well...