Oscar Vargas-Rodriguez
Overview
Explore the profile of Oscar Vargas-Rodriguez including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
35
Citations
444
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Awawdeh A, Tapia A, Alshawi S, Dawodu O, Gaier S, Specht C, et al.
Nucleic Acids Res
. 2024 Nov;
52(22):14244-14259.
PMID: 39558163
Mutations that introduce premature termination codons (PTCs) within protein-coding genes are associated with incurable and severe genetic diseases. Many PTC-associated disorders are life-threatening and have no approved medical treatment options....
2.
Radecki A, Fantasia-Davis A, Maldonado J, Mann J, Sepulveda-Camacho S, Morosky P, et al.
IUBMB Life
. 2024 Oct;
76(12):1139-1153.
PMID: 39417753
Aminoacyl-tRNA synthetases (aaRSs) are universally essential enzymes that synthesize aminoacyl-tRNA substrates for protein synthesis. Although most organisms require a single aaRS gene for each proteinogenic amino acid to translate their...
3.
Douglas J, Cui H, Perona J, Vargas-Rodriguez O, Tyynismaa H, Carreno C, et al.
IUBMB Life
. 2024 Sep;
76(12):1091-1105.
PMID: 39247978
The aminoacyl-tRNA synthetases (aaRS) are a large group of enzymes that implement the genetic code in all known biological systems. They attach amino acids to their cognate tRNAs, moonlight in...
4.
Schuntermann D, Jaskolowski M, Reynolds N, Vargas-Rodriguez O
J Biol Chem
. 2024 Aug;
300(9):107679.
PMID: 39154912
Transfer RNAs (tRNA) are essential small non-coding RNAs that enable the translation of genomic information into proteins in all life forms. The principal function of tRNAs is to bring amino...
5.
Cruz E, Vargas-Rodriguez O
Front Microbiol
. 2024 Aug;
15:1437528.
PMID: 39101037
The rules of the genetic code are implemented by the unique features that define the amino acid identity of each transfer RNA (tRNA). These features, known as "identity elements," mark...
6.
Awawdeh A, Radecki A, Vargas-Rodriguez O
Front Genet
. 2024 May;
15:1420331.
PMID: 38798701
Suppressor transfer RNAs (sup-tRNAs) are receiving renewed attention for their promising therapeutic properties in treating genetic diseases caused by nonsense mutations. Traditionally, sup-tRNAs have been created by replacing the anticodon...
7.
Thaenert A, Sevostyanova A, Chung C, Vargas-Rodriguez O, Melnikov S, Soll D
Proc Natl Acad Sci U S A
. 2024 Mar;
121(11):e2321700121.
PMID: 38442159
Ribosomes are often used in synthetic biology as a tool to produce desired proteins with enhanced properties or entirely new functions. However, repurposing ribosomes for producing designer proteins is challenging...
8.
Schuntermann D, Fischer J, Bile J, Gaier S, Shelley B, Awawdeh A, et al.
J Biol Chem
. 2023 May;
299(7):104852.
PMID: 37224963
The correct coupling of amino acids with transfer RNAs (tRNAs) is vital for translating genetic information into functional proteins. Errors during this process lead to mistranslation, where a codon is...
9.
Morosky P, Comyns C, Nunes L, Chung C, Hoffmann P, Soll D, et al.
Front Mol Biosci
. 2023 Feb;
10:1096261.
PMID: 36762212
Post-translational modifications (PTMs) can occur on almost all amino acids in eukaryotes as a key mechanism for regulating protein function. The ability to study the role of these modifications in...
10.
Krahn N, Soll D, Vargas-Rodriguez O
Front Physiol
. 2022 Sep;
13:983245.
PMID: 36060688
Intricate evolutionary events enabled the emergence of the full set of aminoacyl-tRNA synthetase (aaRS) families that define the genetic code. The diversification of aaRSs has continued in organisms from all...