Osamu Sugiyama
Overview
Explore the profile of Osamu Sugiyama including associated specialties, affiliations and a list of published articles.
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51
Citations
540
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Recent Articles
1.
Sarkar A, Gallo M, Bell J, Mayfield C, Ball J, Ayad M, et al.
Bioengineering (Basel)
. 2025 Jan;
12(1).
PMID: 39851303
regional gene therapy is a promising tissue-engineering strategy for bone regeneration: osteogenic mesenchymal stem cells (MSCs) can be genetically modified to express an osteoinductive stimulus (e.g., bone morphogenetic protein-2), seeded...
2.
Tsutsumi T, Fukuyama K, Kishimoto K, Mori Y, Sugiyama O, Yamamoto G, et al.
BJA Open
. 2024 Aug;
11:100301.
PMID: 39104827
Background: The damage that may be caused to the operating table and patients under general anaesthesia when a large earthquake occurs is unclear. We aimed to evaluate the movement and...
3.
Bougioukli S, Chateau M, Morales H, Vakhshori V, Sugiyama O, Oakes D, et al.
Gene Ther
. 2024 Aug;
31(9-10):527.
PMID: 39090205
No abstract available.
4.
Uneno Y, Fukuyama K, Nishimura A, Eguchi K, Kojima H, Umino T, et al.
Cureus
. 2024 May;
16(4):e58611.
PMID: 38770482
Background and objective Implementing electronic patient-reported outcomes (ePROs) in oncology practice has shown substantial clinical benefits. However, it can be challenging in routine practice, warranting strategies to adapt to different...
5.
Bell J, Collon K, Mayfield C, Gallo M, Chang S, Sugiyama O, et al.
Gene Ther
. 2023 Aug;
30(12):826-834.
PMID: 37568039
Ex-vivo gene therapy has been shown to be an effective method for treating bone defects in pre-clinical models. As gene therapy is explored as a potential treatment option in humans,...
6.
Nishio M, Matsuo H, Kurata Y, Sugiyama O, Fujimoto K
Cancers (Basel)
. 2023 Mar;
15(5).
PMID: 36900325
We aimed to develop and evaluate an automatic prediction system for grading histopathological images of prostate cancer. A total of 10,616 whole slide images (WSIs) of prostate tissue were used...
7.
Collon K, Bell J, Gallo M, Chang S, Bougioukli S, Sugiyama O, et al.
Gene Ther
. 2022 Oct;
30(3-4):369-376.
PMID: 36216880
Human adipose-derived mesenchymal stem cells (ASCs) transduced with a lentiviral vector system to express bone morphogenetic protein 2 (LV-BMP-2) have been shown to reliably heal bone defects in animal models....
8.
Collon K, Bell J, Chang S, Gallo M, Sugiyama O, Marks C, et al.
J Biomed Mater Res A
. 2022 Aug;
110(12):1944-1952.
PMID: 35950648
Small animal models have demonstrated the efficacy of ex vivo regional gene therapy using scaffolds loaded with BMP-2-expressing mesenchymal stem cells (MSCs). Prior to clinical translation, optimization of seeding techniques...
9.
Collon K, Gallo M, Bell J, Chang S, Rodman J, Sugiyama O, et al.
Hum Gene Ther
. 2022 Jul;
33(23-24):1260-1268.
PMID: 35859364
Lentiviral transduction of human mesenchymal stem cells (MSCs) induces long-term transgene expression and holds great promise for multiple gene therapy applications. Polybrene is the most commonly used reagent to improve...
10.
Shimoto M, Cho K, Kurata M, Hitomi M, Kato Y, Aida S, et al.
Disaster Med Public Health Prep
. 2022 Apr;
:1-3.
PMID: 35414371
During the 2016 Kumamoto earthquake, 10 hospitals took responsibility for complete evacuation, in what has become regarded as one of the largest evacuations of patients in 1 seismic disaster. We...