Orsolya Kolacsek
Overview
Explore the profile of Orsolya Kolacsek including associated specialties, affiliations and a list of published articles.
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Articles
15
Citations
138
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0
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Recent Articles
1.
Ree D, Fothi A, Varga N, Kolacsek O, Orban T, Apati A
Genes (Basel)
. 2022 Nov;
13(11).
PMID: 36360162
Maturation of microRNAs (miRNAs) begins by the "Microprocessor" complex, containing the Drosha endonuclease and its partner protein, "DiGeorge Syndrome Critical Region 8" (DGCR8). Although the main function of the two...
2.
Rasko T, Pande A, Radscheit K, Zink A, Singh M, Sommer C, et al.
Mol Biol Evol
. 2022 Oct;
39(10).
PMID: 36205081
Although new genes can arrive from modes other than duplication, few examples are well characterized. Given high expression in some human brain subregions and a putative link to psychological disorders...
3.
Kolacsek O, Wachtl G, Fothi A, Schamberger A, Sandor S, Pergel E, et al.
Gene
. 2022 May;
834:146609.
PMID: 35609796
Transposable elements are widespread in all living organisms. In addition to self-reproduction, they are a major source of genetic variation that drives genome evolution but our knowledge of the functions...
4.
Kolacsek O, Orban T
Gene
. 2018 Jul;
676:184-188.
PMID: 30021132
Sleeping Beauty (SB) transposon based technology has been extensively applied in basic research and biotechnology for routine cell culture gene delivery and vertebrate transgenesis, and it is also investigated in...
5.
Szabo Z, Heja L, Szalay G, Kekesi O, Furedi A, Szebenyi K, et al.
Sci Rep
. 2017 Jul;
7(1):6018.
PMID: 28729692
Slow wave activity (SWA) is a characteristic brain oscillation in sleep and quiet wakefulness. Although the cell types contributing to SWA genesis are not yet identified, the principal role of...
6.
Kolacsek O, Pergel E, Varga N, Apati A, Orban T
Gene
. 2016 Nov;
598:43-49.
PMID: 27794495
There are numerous applications of quantitative PCR for both diagnostic and basic research. As in many other techniques the basis of quantification is that comparisons are made between different (unknown...
7.
Jemnitz K, Batai-Konczos A, Szabo M, Ioja E, Kolacsek O, Orban T, et al.
Toxicol In Vitro
. 2016 Oct;
38:159-169.
PMID: 27717685
Increasing number of papers demonstrate that Kupffer cells (KCs) play a role in the development of drug induced liver injury (DILI). Furthermore, elevated intracellular Ca level of hepatocytes is considered...
8.
Szebenyi K, Furedi A, Kolacsek O, Pergel E, Bosze Z, Bender B, et al.
Sci Rep
. 2015 Aug;
5:12645.
PMID: 26234466
In drug discovery, prediction of selectivity and toxicity require the evaluation of cellular calcium homeostasis. The rat is a preferred laboratory animal for pharmacology and toxicology studies, while currently no...
9.
Szebenyi K, Furedi A, Kolacsek O, Csohany R, Prokai A, Kis-Petik K, et al.
J Am Soc Nephrol
. 2015 Mar;
26(11):2731-40.
PMID: 25788535
Intrarenal changes in cytoplasmic calcium levels have a key role in determining pathologic and pharmacologic responses in major kidney diseases. However, cell-specific delivery of calcium-sensitive probes in vivo remains problematic....
10.
Kolacsek O, Erdei Z, Apati A, Sandor S, Izsvak Z, Ivics Z, et al.
Hum Gene Ther Methods
. 2014 Jul;
25(4):241-52.
PMID: 25045962
The Sleeping Beauty (SB) and piggyBac (PB) DNA transposons represent an emerging new gene delivery technology, potentially suitable for human gene therapy applications. Previous studies pointed to important differences between...