Orquidea Ribeiro
Overview
Explore the profile of Orquidea Ribeiro including associated specialties, affiliations and a list of published articles.
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Articles
31
Citations
379
Followers
0
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Recent Articles
1.
Johansson N, Dreano L, Vidilaseris K, Khattab A, Liu J, Lasbleiz A, et al.
ChemMedChem
. 2021 Aug;
16(21):3360-3367.
PMID: 34459148
Inhibition of membrane-bound pyrophosphatase (mPPase) with small molecules offer a new approach in the fight against pathogenic protozoan parasites. mPPases are absent in humans, but essential for many protists as...
2.
Moreira S, Baptista J, Goncalves-Pereira J, Pereira J, Ribeiro O, Dias C, et al.
Eur Geriatr Med
. 2021 Mar;
12(5):1057-1064.
PMID: 33646536
Purpose: Older patients are the fastest expanding subgroup of intensive care units (ICU) and are particularly susceptible to bacterial infections and sepsis. The aim of this study was to address...
3.
Vakirlis N, Monerawela C, McManus G, Ribeiro O, McLysaght A, James T, et al.
Yeast
. 2019 Apr;
36(7):425-437.
PMID: 30963617
The sequencing of over a thousand Saccharomyces cerevisiae genomes revealed a complex pangenome. Over one third of the discovered genes are not present in the S. cerevisiae core genome but...
4.
Ehsan M, Ghani L, Du Y, Hariharan P, Mortensen J, Ribeiro O, et al.
Analyst
. 2017 Sep;
142(20):3889-3898.
PMID: 28913526
Integral membrane proteins either alone or as complexes carry out a range of key cellular functions. Detergents are indispensable tools in the isolation of membrane proteins from biological membranes for...
5.
Hussain H, Mortensen J, Du Y, Santillan C, Ribeiro O, Go J, et al.
Sci Rep
. 2017 Jun;
7(1):3963.
PMID: 28638082
High-resolution membrane protein structures are essential for understanding the molecular basis of diverse biological events and important in drug development. Detergents are usually used to extract these bio-macromolecules from the...
6.
Das M, Du Y, Mortensen J, Ribeiro O, Hariharan P, Guan L, et al.
Chem Sci
. 2017 Apr;
8(2):1169-1177.
PMID: 28451257
Amphiphile selection is a crucial step in membrane protein structural and functional study. As conventional detergents have limited scope and utility, novel agents with enhanced efficacy need to be developed....
7.
Hussain H, Du Y, Tikhonova E, Mortensen J, Ribeiro O, Santillan C, et al.
Chemistry
. 2017 Mar;
23(28):6724-6729.
PMID: 28303608
As a membrane-mimetic system, detergent micelles are popularly used to extract membrane proteins from lipid environments and to maintain their solubility and stability in an aqueous medium. However, many membrane...
8.
Das M, Du Y, Ribeiro O, Hariharan P, Mortensen J, Patra D, et al.
J Am Chem Soc
. 2017 Feb;
139(8):3072-3081.
PMID: 28218862
Detergents are essential tools for functional and structural studies of membrane proteins. However, conventional detergents are limited in their scope and utility, particularly for eukaryotic membrane proteins. Thus, there are...
9.
Cho K, Ribeiro O, Du Y, Tikhonova E, Mortensen J, Markham K, et al.
Chemistry
. 2016 Oct;
22(52):18833-18839.
PMID: 27743406
Detergents serve as useful tools for membrane protein structural and functional studies. Their amphipathic nature allows detergents to associate with the hydrophobic regions of membrane proteins whilst maintaining the proteins...
10.
Bae H, Mortensen J, Ribeiro O, Du Y, Ehsan M, Kobilka B, et al.
Chem Commun (Camb)
. 2016 Oct;
52(81):12104-12107.
PMID: 27711401
A novel class of detergents, designated tandem neopentyl glycol maltosides (TNMs), were evaluated with four target membrane proteins. The best detergent varied depending on the target, but TNM-C12L and TNM-C11S...