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Omar Itani

Explore the profile of Omar Itani including associated specialties, affiliations and a list of published articles. Areas
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Articles 16
Citations 107
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Recent Articles
1.
Willim J, Woike D, Greene D, Das S, Pfeifer K, Yuan W, et al.
Nat Commun . 2024 Sep; 15(1):7909. PMID: 39256359
Members of the leucine rich repeat (LRR) and PDZ domain (LAP) protein family are essential for animal development and histogenesis. Densin-180, encoded by LRRC7, is the only LAP protein selectively...
2.
Read C, Hughes M, Itani O
Am Surg . 2023 Sep; 89(12):6393-6395. PMID: 37698018
This report details the first known case of co-occurrence of gastrointestinal stromal tumor (GIST), pancreatic adenocarcinoma, and gastric adenocarcinoma in an individual with no identifiable genetic abnormalities. The patient is...
3.
Schneider A, Itani O, Cronin E, Daur N, Bucher D, Nadim F
bioRxiv . 2023 Jun; PMID: 37383946
Ionic current levels of identified neurons vary substantially across individual animals. Yet, under similar conditions, neural circuit output can be remarkably similar, as evidenced in many motor systems. All neural...
4.
Li X, Itani O, Bucher D, Rotstein H, Nadim F
bioRxiv . 2023 Jan; PMID: 36712051
Neurons in oscillatory networks often exhibit membrane potential resonance, a peak impedance at a non-zero input frequency. In electrically coupled oscillatory networks, the coupling coefficient (the ratio of post- and...
5.
Patel V, Sarkar P, Siegel D, Teegala S, Hirschberg P, Wajid H, et al.
Diabetes . 2022 Dec; 72(8):1144-1153. PMID: 36525384
Perifornical hypothalamus (PFH) orexin glucose-inhibited (GI) neurons that facilitate arousal have been implicated in hypoglycemia awareness. Mice lacking orexin exhibit narcolepsy, and orexin mediates the effect of the antinarcolepsy drug...
6.
Schneider A, Itani O, Bucher D, Nadim F
eNeuro . 2022 Jul; PMID: 35853725
In similar states, neural circuits produce similar outputs across individuals despite substantial interindividual variability in neuronal ionic conductances and synapses. Circuit states are largely shaped by neuromodulators that tune ionic...
7.
Hemphill C, Pylarinou-Sinclair E, Itani O, Scott B, Crowder C, Van Gilst M
PLoS Genet . 2022 May; 18(5):e1009672. PMID: 35622856
In C. elegans, germline ablation leads to long life span and stress resistance. It has been reported that mutations that block oogenesis or an upstream step in germline development confer...
8.
Schneider A, Fox D, Itani O, Golowasch J, Bucher D, Nadim F
eNeuro . 2021 Oct; 8(6). PMID: 34593519
In oscillatory circuits, some actions of neuromodulators depend on the oscillation frequency. However, the mechanisms are poorly understood. We explored this problem by characterizing neuromodulation of the lateral pyloric (LP)...
9.
Boulin T, Itani O, El Mouridi S, Leclercq-Blondel A, Gendrel M, Macnamara E, et al.
Mol Genet Metab . 2021 Aug; 134(1-2):195-202. PMID: 34412939
Neurobeachin (NBEA) was initially identified as a candidate gene for autism. Recently, variants in NBEA have been associated with neurodevelopmental delay and childhood epilepsy. Here, we report on a novel...
10.
Jouhar L, Jaafar R, Nasreddine R, Itani O, Haddad F, Rizk N, et al.
Int Wound J . 2020 Aug; 17(6):1764-1773. PMID: 32779355
Diabetic Foot Infection (DFI) is a challenging complication of diabetes mellitus with a high burden in the Middle East where there is a marked increase in diabetes prevalence and complications....