Om V Singh
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Explore the profile of Om V Singh including associated specialties, affiliations and a list of published articles.
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Articles
49
Citations
737
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Recent Articles
1.
Singh M, Apshingekar P, Gandhi S, Singh O
Front Med Technol
. 2024 Dec;
6:1486318.
PMID: 39736921
This article provides a high-level overview of US regulatory review and approval processes for the growing field of medical combination products (CPs; those merging drugs with devices and/or biological products)....
2.
Santra S, Kukreja P, Saxena K, Gandhi S, Singh O
Front Med Technol
. 2024 Dec;
6:1473350.
PMID: 39669903
In recent years, the Artificial Intelligence (AI) has enabled conventional Combination Devices (CDs) to innovate in healthcare merging with technology sectors. However, the challenges like reliance on predicate devices in...
3.
Josephs-Spaulding J, Singh O
Front Med Technol
. 2022 Jan;
2:587352.
PMID: 35047882
The emergence of multidrug-resistant (MDR) bacteria threatens humans in various health sectors, including medical devices. Since formal classifications for medical device sterilization and disinfection were established in the 1970's, microbial...
4.
Bala S, Yellamanda K, Kadari A, Ravinuthala V, Kattula B, Singh O, et al.
Bioorg Chem
. 2021 Jul;
115:105185.
PMID: 34329997
Methionine aminopeptidases (MetAPs) are an important class of enzymes that work co-translationally for the removal of initiator methionine. Chemical inhibition or gene knockdown is lethal to the microbes suggesting that...
5.
Beeler E, Choy N, Franks J, Mulcahy F, Singh O
J Nanosci Nanotechnol
. 2019 Sep;
20(3):1567-1577.
PMID: 31492319
Bio-nanotechnology offers eco-friendly processes for the synthesis of stable nanoparticles (NPs). We hypothesized that microorganisms isolated from the root nodules of leguminous plants would biosynthesize silver (Ag) bio-nanoparticles. Clover root...
6.
Kalisha Vali Y, Gundla R, Singh O, Tamboli Y, Di Cesare Manelli L, Ghelardini C, et al.
Bioorg Chem
. 2019 Sep;
92:103210.
PMID: 31473472
A novel series of 4-oxo-spirochromane bearing primary sulfonamide group were synthetized as Carbonic Anhydrase inhibitors (CAIs) and tested for their management of neuropathic pain. Indeed, CAs have been recently validated...
7.
Woappi Y, Singh O
Br Microbiol Res J
. 2019 Aug;
15(3).
PMID: 31456935
Major shifts in intestinal commensal bacteria often result in changes in CD4 T lymphocyte populations, leading to an influx of Th17 cells, chronic inflammation, and eventually cancer. Consequently, the inappropriate...
8.
Cole M, Singh O
J Food Sci Technol
. 2018 Jul;
55(7):2600-2609.
PMID: 30042576
Foodborne pathogens, such as and , are commonly prevalent in contaminated food products seen through annual food recalls. Excessive use of antibiotics through the past few decades has led to...
9.
Beeler E, Singh O
World J Microbiol Biotechnol
. 2016 Jul;
32(9):156.
PMID: 27465856
Industrial use of nanotechnology in daily life has produced an emphasis on the safe and efficient production of nanoparticles (NPs). Traditional chemical oxidation and reduction methods are seen as inefficient,...
10.
Josephs-Spaulding J, Beeler E, Singh O
Appl Microbiol Biotechnol
. 2016 Apr;
100(11):4845-63.
PMID: 27102132
As food safety advances, there is a great need to maintain, distribute, and provide high-quality food to a much broader consumer base. There is also an ever-growing "arms race" between...