Olivier Giger
Overview
Explore the profile of Olivier Giger including associated specialties, affiliations and a list of published articles.
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Articles
20
Citations
168
Followers
0
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Recent Articles
1.
Chen H, Mueller N, Stott K, Kapeni C, Rivers E, Sauer C, et al.
EMBO Mol Med
. 2024 Sep;
16(11):3026.
PMID: 39322863
No abstract available.
2.
Chen H, Mueller N, Stott K, Kapeni C, Rivers E, Sauer C, et al.
EMBO Mol Med
. 2024 Aug;
16(9):2233-2261.
PMID: 39169164
We have developed and validated a highly specific, versatile antibody to the extracellular domain of human LGR5 (α-LGR5). α-LGR5 detects LGR5 overexpression in >90% of colorectal cancer (CRC), hepatocellular carcinoma...
3.
Ng A, McClurg D, Wesley B, Zamani S, Black E, Miremadi A, et al.
Nat Commun
. 2024 May;
15(1):4533.
PMID: 38806493
No abstract available.
4.
Ng A, McClurg D, Wesley B, Zamani S, Black E, Miremadi A, et al.
Nat Commun
. 2024 May;
15(1):4074.
PMID: 38744814
Esophageal adenocarcinoma is a prominent example of cancer characterized by frequent amplifications in oncogenes. However, the mechanisms leading to amplicons that involve breakage-fusion-bridge cycles and extrachromosomal DNA are poorly understood....
5.
Fewings E, Khoo Sert Kim S, Larionov A, Marker A, Giger O, Shaw A, et al.
Endocr Oncol
. 2023 Jul;
1(1):33-44.
PMID: 37435187
Background: Malignant oncocytic adrenocortical neoplasms (OANs) are rare tumours with a distinctive biological behaviour compared to conventional adrenocortical carcinoma (ACC). The current prognostic systems overestimate the malignant potential of these...
6.
Smyth E, Cozens K, Griffiths D, Clark K, Ewings S, Petty R, et al.
BMC Cancer
. 2022 Sep;
22(1):946.
PMID: 36050653
Background: For patients with oesophagogastric adenocarcinoma, surgery is the only curative option and despite the use of multimodality therapy, which combines it with chemotherapy and/or radiotherapy, more than 50% of...
7.
Cheah S, Bisambar C, Pitfield D, Giger O, Ten Hoopen R, Martin J, et al.
Endocrinol Diabetes Metab Case Rep
. 2021 May;
2021.
PMID: 33960322
Summary: A 38-year-old female was identified as carrying a heterozygous pathogenic MEN1 variant (c.1304delG) through predictive genetic testing, following a diagnosis of familial hyperparathyroidism. Routine screening for parathyroid and pituitary...
8.
Whitworth J, Casey R, Smith P, Giger O, Martin J, Clark G, et al.
Eur J Hum Genet
. 2021 Apr;
29(7):1139-1145.
PMID: 33854214
Gastrointestinal stromal tumour (GIST) is a mesenchymal neoplasm arising in the gastrointestinal tract. A rare subset of GISTs are classified as wild-type GIST (wtGIST) and these are frequently associated with...
9.
Aloj L, Giger O, Mendichovszky I, Challis B, Ronel M, Harper I, et al.
EJNMMI Res
. 2021 Jan;
11(1):5.
PMID: 33443647
Background: [ Ga]Ga-DOTATATE PET/CT is now recognised as the most sensitive functional imaging modality for the diagnosis of well-differentiated neuroendocrine tumours (NET) and can inform treatment with peptide receptor radionuclide...
10.
MacFarlane J, Seong K, Bisambar C, Madhu B, Allinson K, Marker A, et al.
Clin Endocrinol (Oxf)
. 2020 Jul;
93(5):528-538.
PMID: 32686200
The citric acid cycle, also known as the Krebs cycle, plays an integral role in cellular metabolism and aerobic respiration. Mutations in genes encoding the citric acid cycle enzymes succinate...