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Olivia Larne

Explore the profile of Olivia Larne including associated specialties, affiliations and a list of published articles. Areas
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Articles 12
Citations 269
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Recent Articles
1.
Jenvert R, Larne O, Johansson A, Berglin M, Pedersen E, Johansson H
Front Toxicol . 2024 Mar; 6:1320367. PMID: 38533186
Biocompatibility testing of medical devices is governed by the ISO 10993 series of standards and includes evaluation of skin sensitization potential of the final product. A majority of all medical...
2.
Forreryd A, Gradin R, Larne O, Rajapakse N, Deag E, Johansson H
ALTEX . 2022 Nov; 40(3):425-438. PMID: 36343115
New approach methodologies (NAMs) for hazard identification of skin sensitizing chemicals were adopted as test guidelines by the OECD during the last decade. These alternatives to animal models align to...
3.
Gradin R, Johansson A, Forreryd A, Aaltonen E, Jerre A, Larne O, et al.
Toxicol Sci . 2020 May; 176(2):423-432. PMID: 32421796
Proactive identification and characterization of hazards attributable to chemicals are central aspects of risk assessments. Current legislations and trends in predictive toxicology advocate a transition from in vivo methods to...
4.
Stevenson M, Czekala L, Simms L, Tschierske N, Larne O, Walele T
Regul Toxicol Pharmacol . 2019 Jan; 103:158-165. PMID: 30629970
Electronic cigarettes (e-cigarettes) are an increasingly popular alternative to combustible tobacco cigarettes among smokers worldwide. A growing body of research indicates that flavours play a critical role in attracting and...
5.
Johansson H, Gradin R, Forreryd A, Agemark M, Zeller K, Johansson A, et al.
ALTEX . 2017 Feb; 34(4):515-523. PMID: 28214915
Chemical hypersensitivity is an immunological response towards foreign substances, commonly referred to as sensitizers, which gives rise primarily to the clinical symptoms known as allergic contact dermatitis. For the purpose...
6.
Larne O, Hagman Z, Lilja H, Bjartell A, Edsjo A, Ceder Y
Carcinogenesis . 2015 May; 36(8):858-66. PMID: 25969144
Androgen signalling through the androgen receptor (AR) is essential for prostate cancer initiation, progression and transformation to the lethal castration-resistant state. The aim of this study was to characterize the...
7.
Larne O, Ostling P, Haflidadottir B, Hagman Z, Aakula A, Kohonen P, et al.
Eur Urol . 2015 Jan; 68(4):581-8. PMID: 25556023
Background: Factors affecting serum prostate-specific antigen (PSA) levels in men are clinically important, but apart from effects mediated through the androgen receptor, they are poorly understood. Objective: To investigate whether...
8.
Haflidadottir B, Larne O, Martin M, Persson M, Edsjo A, Bjartell A, et al.
PLoS One . 2013 Aug; 8(8):e72400. PMID: 23951320
Aberrant expression of miR-96 in prostate cancer has previously been reported. However, the role and mechanism of action of miR-96 in prostate cancer has not been determined. In this study,...
9.
Larne O, Martens-Uzunova E, Hagman Z, Edsjo A, Lippolis G, den Berg M, et al.
Int J Cancer . 2012 Nov; 132(12):2867-75. PMID: 23184647
Today, the majority of prostate tumors are detected at early stages with uncertain prognosis. Therefore, we set out to identify early predictive markers of prostate cancer with aggressive progression characteristics....
10.
Hagman Z, Larne O, Edsjo A, Bjartell A, Ehrnstrom R, Ulmert D, et al.
Int J Cancer . 2011 Feb; 127(12):2768-76. PMID: 21351256
MicroRNAs (miRNAs) are small noncoding RNAs that post-transcriptionally regulate gene expression. There have been several reports of miRNA deregulation in prostate cancer (PCa) and the biological evidence for an involvement...