Olivereen Le Roux
Overview
Explore the profile of Olivereen Le Roux including associated specialties, affiliations and a list of published articles.
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Articles
4
Citations
26
Followers
0
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Recent Articles
1.
Castro-Pando S, Howell R, Li L, Mascaro M, Faraoni E, Le Roux O, et al.
Cancer Immunol Res
. 2024 Jun;
12(9):1170-1183.
PMID: 38842383
IL17 is required for the initiation and progression of pancreatic cancer, particularly in the context of inflammation, as previously shown by genetic and pharmacological approaches. However, the cellular compartment and...
2.
Chandra V, Li L, Le Roux O, Zhang Y, Howell R, Rupani D, et al.
Cancer Cell
. 2023 Dec;
42(1):85-100.e6.
PMID: 38157865
Microbes influence cancer initiation, progression and therapy responsiveness. IL-17 signaling contributes to gut barrier immunity by regulating microbes but also drives tumor growth. A knowledge gap remains regarding the influence...
3.
Faraoni E, Singh K, Chandra V, Le Roux O, Dai Y, Sahin I, et al.
Cancer Res
. 2023 Jan;
83(7):1111-1127.
PMID: 36720042
Significance: Ductal-derived pancreatic tumors have elevated epithelial and CD8+GZM+ T-cell CD73 expression that confers sensitivity to small-molecule inhibition of CD73 or Adora2b to promote CD8+ T-cell-mediated tumor regression. See related...
4.
Rupani D, Thege F, Chandra V, Rajaei H, Cowan R, Wormann S, et al.
Development
. 2022 Dec;
150(2).
PMID: 36458554
Adenosine deaminase acting on RNA 1 (ADAR1) is an RNA-binding protein that deaminates adenosine (A) to inosine (I). A-to-I editing alters post-transcriptional RNA processing, making ADAR1 a crucial regulator of...