Oliver H Tam
Overview
Explore the profile of Oliver H Tam including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
18
Citations
2007
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0
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Recent Articles
1.
ONeill K, Shaw R, Bolger I, Tam O, Phatnani H, Gale Hammell M
Cell Rep
. 2025 Mar;
44(3):115402.
PMID: 40067829
Amyotrophic lateral sclerosis (ALS) is a complex syndrome with multiple genetic causes and wide variation in disease presentation. Despite this heterogeneity, large-scale genomics studies revealed that ALS postmortem samples can...
2.
Arnold F, Cui Y, Michels S, Colwin M, Stockford C, Ye W, et al.
bioRxiv
. 2024 Feb;
PMID: 38328178
Nuclear clearance and cytoplasmic aggregation of the RNA-binding protein TDP-43 are observed in many neurodegenerative disorders, including amyotrophic lateral sclerosis (ALS) and fronto- temporal dementia (FTD). Although TDP-43 dysregulation of...
3.
Rupert D, Nowlan A, Tam O, Gale Hammell M
PLoS Comput Biol
. 2020 May;
16(5):e1007754.
PMID: 32379823
The current academic culture facing women in science, technology, engineering, and math (STEM) fields in the United States has sparked the formation of grassroots advocacy groups to empower female scientists...
4.
Tam O, Rozhkov N, Shaw R, Kim D, Hubbard I, Fennessey S, et al.
Cell Rep
. 2019 Oct;
29(5):1164-1177.e5.
PMID: 31665631
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by the progressive loss of motor neurons. While several pathogenic mutations have been identified, the vast majority of ALS cases...
5.
Tam O, Ostrow L, Gale Hammell M
Mob DNA
. 2019 Aug;
10:32.
PMID: 31372185
Transposable Elements (TEs) are mobile genetic elements whose sequences constitute nearly half of the human genome. Each TE copy can be present in hundreds to thousands of locations within the...
6.
Okamura E, Tam O, Posfai E, Li L, Cockburn K, Lee C, et al.
Dev Biol
. 2019 Jul;
455(2):382-392.
PMID: 31315026
Estrogen related receptor beta (Esrrb) is an orphan nuclear receptor that is required for self-renewal and pluripotency in mouse embryonic stem (ES) cells. However, in the early post-implantation mouse embryo,...
7.
DeMille D, Carlston C, Tam O, Palumbos J, Stalker H, Mao R, et al.
Am J Med Genet A
. 2018 Mar;
176(4):945-950.
PMID: 29575629
Connexin 26 (Cx26), encoded by the GJB2 gene, is a key protein involved in the formation of gap junctions in epithelial organs including the inner ear and palmoplantar epidermis. Pathogenic...
8.
Tam O, Pennisi D, Wilkinson L, Little M, Wazin F, Wan V, et al.
Exp Eye Res
. 2018 Feb;
170:58-66.
PMID: 29458060
The development and growth of the vertebrate ocular lens is dependent on the regulated proliferation of an anterior monolayer of epithelial cells, and their subsequent differentiation into elongate fiber cells....
9.
Petsch K, Manzotti P, Tam O, Meeley R, Hammell M, Consonni G, et al.
Plant Cell
. 2015 Jul;
27(8):2163-77.
PMID: 26209554
Dicer enzymes function at the core of RNA silencing to defend against exogenous RNA or to regulate endogenous genes. Plant DICER-LIKE4 (DCL4) performs dual functions, acting in antiviral defense and...
10.
Jin Y, Tam O, Paniagua E, Hammell M
Bioinformatics
. 2015 Jul;
31(22):3593-9.
PMID: 26206304
Motivation: Most RNA-seq data analysis software packages are not designed to handle the complexities involved in properly apportioning short sequencing reads to highly repetitive regions of the genome. These regions...