Olga V Efremenkova
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Explore the profile of Olga V Efremenkova including associated specialties, affiliations and a list of published articles.
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19
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184
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Recent Articles
11.
Negrya S, Jasko M, Solyev P, Karpenko I, Efremenkova O, Vasilyeva B, et al.
J Antibiot (Tokyo)
. 2020 Jan;
73(4):236-246.
PMID: 31932744
Recently we have synthesized a set of pyrimidine nucleoside derivatives bearing extended alkyltriazolylmethyl substituents at position 5 of the nucleic base, and showed their significant activity against Mycobacterium tuberculosis virulent...
12.
Negrya S, Efremenkova O, Solyev P, Chekhov V, Ivanov M, Sumarukova I, et al.
J Antibiot (Tokyo)
. 2019 Feb;
72(7):535-544.
PMID: 30792519
The emergence of new drug-resistant strains of bacteria necessitates the development of principally new antibacterial agents. One of the novel classes of antibacterial agents is nucleoside analogs. We have developed...
13.
Khandazhinskaya A, Alexandrova L, Matyugina E, Solyev P, Efremenkova O, Buckheit K, et al.
Molecules
. 2018 Nov;
23(12).
PMID: 30477147
A series of novel 5'-norcarbocyclic derivatives of 5-alkoxymethyl or 5-alkyltriazolyl-methyl uracil were synthesized and the activity of the compounds evaluated against both Gram-positive and Gram-negative bacteria. The growth of was...
14.
Glukhova A, Karabanova A, Yakushev A, Semenyuk I, Boykova Y, Malkina N, et al.
Antibiotics (Basel)
. 2018 Nov;
7(4).
PMID: 30380603
Because of the spread of drug resistance, it is necessary to look for new antibiotics that are effective against pathogenic microorganisms. The purpose of this study was to analyse the...
15.
Tyurin A, Alferova V, Paramonov A, Shuvalov M, Malanicheva I, Grammatikova N, et al.
Medchemcomm
. 2018 Aug;
9(4):667-675.
PMID: 30108957
The study of an archived sample of crystallomycin complex using HPLC, ESI HRMS, and 2D NMR showed that two major components of the antibiotic, compounds and , are lipopeptides having...
16.
Osterman I, Komarova E, Shiryaev D, Korniltsev I, Khven I, Lukyanov D, et al.
Antimicrob Agents Chemother
. 2016 Oct;
60(12):7481-7489.
PMID: 27736765
In order to accelerate drug discovery, a simple, reliable, and cost-effective system for high-throughput identification of a potential antibiotic mechanism of action is required. To facilitate such screening of new...
17.
Polikanov Y, Osterman I, Szal T, Tashlitsky V, Serebryakova M, Kusochek P, et al.
Mol Cell
. 2014 Oct;
56(4):531-40.
PMID: 25306919
We demonstrate that the antibiotic amicoumacin A (AMI) is a potent inhibitor of protein synthesis. Resistance mutations in helix 24 of the 16S rRNA mapped the AMI binding site to...
18.
Shmalenyuk E, Chernousova L, Karpenko I, Kochetkov S, Smirnova T, Andreevskaya S, et al.
Bioorg Med Chem
. 2013 Jul;
21(17):4874-84.
PMID: 23891229
Two sets of pyrimidine nucleoside derivatives bearing extended alkyloxymethyl or alkyltriazolidomethyl substituents at position 5 of the nucleobase were synthesized and evaluated as potential antituberculosis agents. The impact of modifications...
19.
Osterman I, Prokhorova I, Sysoev V, Boykova Y, Efremenkova O, Svetlov M, et al.
Antimicrob Agents Chemother
. 2012 Jan;
56(4):1774-83.
PMID: 22252829
A reporter construct was created on the basis of the transcription attenuator region of the Escherichia coli tryptophan operon. Dual-fluorescent-protein genes for red fluorescent protein and cerulean fluorescent protein were...