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Olga E Savelieva

Explore the profile of Olga E Savelieva including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Perelmuter V, Grigoryeva E, Alifanov V, Kalinchuk A, Andryuhova E, Savelieva O, et al.
Int J Mol Sci . 2024 Oct; 25(20). PMID: 39456890
Most studies on CTCs have focused on isolating cells that express EpCAM. In this study, we emphasize the presence of EpCAM-negative and EpCAM CTCs, in addition to EpCAM CTCs, in...
2.
Mekler A, Schwartz D, Savelieva O
Cell Mol Neurobiol . 2023 Dec; 44(1):13. PMID: 38150033
Gliomas, including anaplastic gliomas (AG; grade 3) and glioblastomas (GBM; grade 4), are malignant brain tumors associated with poor prognosis and low survival rates. Current classification systems based on histopathology...
3.
Grigoryeva E, Tashireva L, Savelieva O, Zavyalova M, Popova N, Kuznetsov G, et al.
Int J Mol Sci . 2023 Feb; 24(3). PMID: 36769251
Integrins are cell adhesion receptors, which play a role in breast cancer invasion, angiogenesis, and metastasis. Moreover, it has been shown that exosomal integrins provide organotropic metastasis in a mouse...
4.
Menyailo M, Zainullina V, Khozyainova A, Tashireva L, Zolotareva S, Gerashchenko T, et al.
Adv Biol (Weinh) . 2022 Nov; 7(2):e2200206. PMID: 36449636
Circulating tumor cells and hybrid cells formed by the fusion of tumor cells with normal cells are leading players in metastasis and have prognostic relevance. This study applies single-cell RNA...
5.
Grigoryeva E, Tashireva L, Alifanov V, Savelieva O, Vtorushin S, Zavyalova M, et al.
Int J Mol Sci . 2022 Aug; 23(16). PMID: 36012742
Stemness and epithelial-mesenchymal plasticity are widely studied in the circulating tumor cells of breast cancer patients because the roles of both processes in tumor progression are well established. An important...
6.
Tashireva L, Savelieva O, Grigoryeva E, Nikitin Y, Denisov E, Vtorushin S, et al.
Int J Mol Sci . 2021 Apr; 22(5). PMID: 33801519
To date, there is indisputable evidence of significant CTC heterogeneity in carcinomas, in particular breast cancer. The heterogeneity of CTCs is manifested in the key characteristics of tumor cells related...
7.
Savelieva O, Tashireva L, Kaigorodova E, Buzenkova A, Mukhamedzhanov R, Grigoryeva E, et al.
Int J Mol Sci . 2020 Apr; 21(8). PMID: 32316333
The presence of stem and epithelial-mesenchymal-transition (EMT) features in circulating tumor cells (CTCs) determines their invasiveness, adaptability to the microenvironment, and resistance to proapoptotic signals and chemotherapy. It also allows...
8.
Tashireva L, Zavyalova M, Savelieva O, Gerashchenko T, Kaigorodova E, Denisov E, et al.
Front Oncol . 2020 Mar; 10:50. PMID: 32154161
The identification of tumor cells that can be potential metastatic seeds would reach two key aims-prognosis of metastasis risk and appointment of the optimal adjuvant therapy to prevent metastatic disease....
9.
Perelmuter V, Tashireva L, Savelieva O, Denisov E, Kaigorodova E, Zavyalova M, et al.
Breast Cancer (Dove Med Press) . 2019 Jul; 11:209-219. PMID: 31308736
Chemotherapy, along with surgery and radiotherapy, is a key treatment option for malignant tumors. Neoadjuvant chemotherapy (NACT) reduces the tumor size and enables total tumor resection. In addition, NACT is...
10.
Kaigorodova E, Savelieva O, Tashireva L, Tarabanovskaya N, Simolina E, Denisov E, et al.
Molecules . 2018 Mar; 23(4). PMID: 29565320
The biological properties of circulating tumor cells (CTCs), and their dynamics during neoadjuvant chemotherapy are important, both for disease progression prediction and therapeutic target determination, with the aim of preventing...