Ole Winther
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Explore the profile of Ole Winther including associated specialties, affiliations and a list of published articles.
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89
Citations
6645
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Recent Articles
1.
Moreno J, Nielsen H, Winther O, Teufel F
Bioinformatics
. 2024 Nov;
40(12).
PMID: 39540738
Motivation: Protein subcellular location prediction is a widely explored task in bioinformatics because of its importance in proteomics research. We propose DeepLocPro, an extension to the popular method DeepLoc, tailored...
2.
Thomsen K, Jalaboi R, Winther O, Lomholt H, Lorentzen H, Hogsberg T, et al.
Lasers Surg Med
. 2024 Sep;
57(1):80-87.
PMID: 39308029
Objectives: Hirsutism is a widespread condition affecting 5%-15% of females. Laser treatment of hirsutism has the best long-term effect. Patients with nonpigmented or nonterminal hairs are not eligible for laser...
3.
Odum M, Teufel F, Thumuluri V, Almagro Armenteros J, Johansen A, Winther O, et al.
Nucleic Acids Res
. 2024 Apr;
52(W1):W215-W220.
PMID: 38587188
DeepLoc 2.0 is a popular web server for the prediction of protein subcellular localization and sorting signals. Here, we introduce DeepLoc 2.1, which additionally classifies the input proteins into the...
4.
Lievin V, Hother C, Motzfeldt A, Winther O
Patterns (N Y)
. 2024 Mar;
5(3):100943.
PMID: 38487804
Although large language models often produce impressive outputs, it remains unclear how they perform in real-world scenarios requiring strong reasoning skills and expert domain knowledge. We set out to investigate...
5.
Hoie M, Gade F, Johansen J, Wurtzen C, Winther O, Nielsen M, et al.
Front Immunol
. 2024 Feb;
15:1322712.
PMID: 38390326
Accurate computational identification of B-cell epitopes is crucial for the development of vaccines, therapies, and diagnostic tools. However, current structure-based prediction methods face limitations due to the dependency on experimentally...
6.
Wang J, Horlacher M, Cheng L, Winther O
Bioinformatics
. 2024 Feb;
40(2).
PMID: 38317052
Motivation: Accurate prediction of RNA subcellular localization plays an important role in understanding cellular processes and functions. Although post-transcriptional processes are governed by trans-acting RNA binding proteins (RBPs) through interaction...
7.
Teufel F, Gislason M, Almagro Armenteros J, Johansen A, Winther O, Nielsen H
NAR Genom Bioinform
. 2023 Oct;
5(4):lqad088.
PMID: 37850036
When splitting biological sequence data for the development and testing of predictive models, it is necessary to avoid too-closely related pairs of sequences ending up in different partitions. If this...
8.
Teufel F, Refsgaard J, Madsen C, Stahlhut C, Gronborg M, Winther O, et al.
Bioinformatics
. 2023 Oct;
39(10).
PMID: 37812217
Motivation: Peptides are ubiquitous throughout life and involved in a wide range of biological processes, ranging from neural signaling in higher organisms to antimicrobial peptides in bacteria. Many peptides are...
9.
Busk J, Schmidt M, Winther O, Vegge T, Jorgensen P
Phys Chem Chem Phys
. 2023 Sep;
25(37):25828-25837.
PMID: 37724552
Inexpensive machine learning (ML) potentials are increasingly being used to speed up structural optimization and molecular dynamics simulations of materials by iteratively predicting and applying interatomic forces. In these settings,...
10.
Ott S, Hebenstreit K, Lievin V, Hother C, Moradi M, Mayrhauser M, et al.
Sci Data
. 2023 Aug;
10(1):528.
PMID: 37553439
Large language models (LLMs) such as GPT-4 have recently demonstrated impressive results across a wide range of tasks. LLMs are still limited, however, in that they frequently fail at complex...