Olaf Picker
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Explore the profile of Olaf Picker including associated specialties, affiliations and a list of published articles.
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Articles
49
Citations
398
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Recent Articles
1.
Marcus C, Hansen C, Schlimgen C, Eitner-Pchalek J, Schulz J, Hof S, et al.
Int J Mol Sci
. 2024 Sep;
25(17).
PMID: 39273258
Systemic vasodilating agents like nitroglycerin (NG) or iloprost (Ilo) show beneficial effects on intestinal microcirculation during sepsis, which could be attenuated by activation of the sympathetic nervous system or systemic...
2.
Priebe C, Bosse H, Michael M, Picker O, Bernhard M, Tautz J
Anaesthesiologie
. 2024 Sep;
73(10):656-667.
PMID: 39222093
Background: The establishment of a resuscitation room management for nontraumatic critically ill children appears to make sense. This study collected data of pediatric patients suffering from nontraumatic critically ill conditions...
3.
Hof S, Untiedt H, Hubner A, Marcus C, Kuebart A, Herminghaus A, et al.
Sci Rep
. 2024 Jun;
14(1):12960.
PMID: 38839819
The maintenance of intestinal integrity and barrier function under conditions of restricted oxygen availability is crucial to avoid bacterial translocation and local inflammation. Both lead to secondary diseases after hemorrhagic...
4.
Schurmann J, Michael M, Picker O, Bieler D, Heitkotter K, Tremmel T, et al.
Anaesthesiologie
. 2024 May;
73(7):444-453.
PMID: 38777920
Introduction: Penetrating injuries are a rare but recurring emergency situation in the out-of-hospital and in-hospital emergency settings. The purpose of this study was to determine the incidence and characteristics of...
5.
Hof S, Lingens L, Michels M, Marcus C, Kuebart A, Herminghaus A, et al.
Front Immunol
. 2024 Apr;
15:1369617.
PMID: 38566995
Introduction: Hemorrhagic shock is characterized by derangements of the gastrointestinal microcirculation. Topical therapy with nitroglycerine or iloprost improves gastric tissue oxygenation but not regional perfusion, probably due to precapillary adrenergic...
6.
Kuebart A, Gross K, Maicher C, Sonnenschein M, Raupach A, Schulz J, et al.
Int J Mol Sci
. 2024 Jan;
25(1).
PMID: 38203431
Recent studies observed, despite an anti-hyperlipidaemic effect, a positive impact of fibrates on septic conditions. This study evaluates the effects of gemfibrozil on microcirculatory variables, mitochondrial function, and lipid peroxidation...
7.
Kuebart A, Gross K, Ripkens J, Tenge T, Raupach A, Schulz J, et al.
Int J Mol Sci
. 2023 Mar;
24(6).
PMID: 36982530
Microcirculatory and mitochondrial dysfunction are considered the main mechanisms of septic shock. Studies suggest that statins modulate inflammatory response, microcirculation, and mitochondrial function, possibly through their action on peroxisome proliferator-activated...
8.
Hof S, Marcus C, Kuebart A, Schulz J, Truse R, Raupach A, et al.
Front Med (Lausanne)
. 2022 Jun;
9:869372.
PMID: 35652064
Impaired oxygen utilization is the underlying pathophysiological process in different shock states. Clinically most important are septic and hemorrhagic shock, which comprise more than 75% of all clinical cases of...
9.
Hof S, Truse R, Weber L, Herminghaus A, Schulz J, Weber A, et al.
Front Med (Lausanne)
. 2022 May;
9:867298.
PMID: 35573010
Introduction: Acute hemorrhage results in perfusion deficit and regional hypoxia. Since failure of intestinal integrity seem to be the linking element between hemorrhage, delayed multi organ failure, and mortality, it...
10.
Mullebner A, Herminghaus A, Miller I, Kames M, Luis A, Picker O, et al.
Front Med (Lausanne)
. 2022 Apr;
9:785285.
PMID: 35372445
Background: Abdominal surgery is an efficient treatment of intra-abdominal sepsis. Surgical trauma and peritoneal infection lead to the activation of multiple pathological pathways. The liver is particularly susceptible to injury...