Oksana Lockridge
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Explore the profile of Oksana Lockridge including associated specialties, affiliations and a list of published articles.
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180
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2748
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Recent Articles
1.
Girardo B, Yue Y, Lockridge O, Bartling A, Schopfer L, Augusto L, et al.
J Bacteriol
. 2025 Jan;
207(2):e0037724.
PMID: 39846732
Importance: is classified as a Tier 1 select agent due to the low infectious dose, ease of transmission, and potential use as a bioweapon. To better understand the stress defense...
2.
Pashirova T, Shaihutdinova Z, Tatarinov D, Titova A, Malanyeva A, Vasileva O, et al.
Int J Biol Macromol
. 2024 Nov;
282(Pt 6):137305.
PMID: 39515732
Human butyrylcholinesterase (BChE) is an efficient bioscavenger of toxicants. Highly purified BChE was labelled with the near infrared fluorescent IRDye800CW. The goal was to determine the pharmacokinetics and fate of...
3.
Girardo B, Schopfer L, Yue Y, Lockridge O, Larson M
PLoS One
. 2024 Apr;
19(4):e0299701.
PMID: 38683788
Recombinant Francisella tularensis universal stress protein with a C-terminal histidine-tag (rUsp/His6) was expressed in Escherichia coli. Endogenous F. tularensis Usp has a predicted molecular mass of 30 kDa, but rUsp/His6...
4.
Schopfer L, Girardo B, Lockridge O, Larson M
Biochem Res Int
. 2024 Feb;
2024:7120208.
PMID: 38347948
Bacterial and mammalian cells are rich in putrescine, spermidine, and spermine. Polyamines are required for optimum fitness, but the biological function of these small aliphatic compounds has only been partially...
5.
Masson P, Shaihutdinova Z, Lockridge O
Biochem Pharmacol
. 2023 Nov;
218:115910.
PMID: 37972875
Butyrylcholinesterase (BChE) is present in plasma and numerous cells and organs. Its physiological function(s) is(are) still unclear. However, this enzyme is of pharmacological and toxicological importance. It displays a broad...
6.
Lockridge O, Schopfer L
Chem Biol Interact
. 2023 Mar;
376:110460.
PMID: 36963650
The acute effects of exposure to organophosphorus toxicants are explained by inhibition of acetylcholinesterase activity. However, the mechanisms that explain long term illness associated with organophosphorus exposure are still under...
7.
Lockridge O
Curr Protoc
. 2023 Feb;
3(2):e672.
PMID: 36799690
Adductomics is epidemiology at the molecular level. Untargeted adductomics compares levels of chemical adducts on albumin, hemoglobin, and DNA between healthy and exposed individuals. The goal is to determine a...
8.
Schopfer L, David E, Hinrichs S, Lockridge O
PLoS One
. 2023 Jan;
18(1):e0280380.
PMID: 36638134
Protection from the toxicity of nerve agents is achieved by pretreatment with human butyrylcholinesterase (BChE). Current methods for purifying large quantities of BChE from frozen Cohn fraction IV-4 produce 99%...
9.
Munoz-Torrero D, Schopfer L, Lockridge O
Chem Res Toxicol
. 2023 Jan;
36(1):112-121.
PMID: 36598934
Chronic low-dose exposure to organophosphorus (OP) toxicants is correlated with an increase in the risk of impaired cognition and neurodegenerative diseases. A mechanism to explain this relationship is needed. We...
10.
Schopfer L, Onder S, Lockridge O
Chem Res Toxicol
. 2022 Sep;
35(9):1570-1578.
PMID: 36048166
Exposure to organophosphorus pesticides (OP) can have chronic adverse effects that are independent of inhibition of acetylcholinesterase, the classic target for acute OP toxicity. In pure proteins, the organophosphorus pesticide...