Oberdan Leo
Overview
Explore the profile of Oberdan Leo including associated specialties, affiliations and a list of published articles.
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76
Citations
2837
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Recent Articles
1.
Englebert K, Taquin A, Azouz A, Acolty V, Vande Velde S, Vanhollebeke M, et al.
Cell Rep
. 2024 Feb;
43(3):113824.
PMID: 38386557
Adipose tissue homeostasis relies on the interplay between several regulatory lineages, such as type 2 innate lymphoid cells (ILC2s), T helper 2 (Th2) cells, regulatory T cells, eosinophils, and type...
2.
Bowakim-Anta N, Acolty V, Azouz A, Yagita H, Leo O, Goriely S, et al.
Front Immunol
. 2023 Mar;
14:1023064.
PMID: 36993956
Introduction: Most T lymphocytes, including regulatory T cells, express the CD27 costimulatory receptor in steady state conditions. There is evidence that CD27 engagement on conventional T lymphocytes favors the development...
3.
Bisilliat Donnet C, Acolty V, Azouz A, Taquin A, Henin C, Trusso Cafarello S, et al.
Cancer Immunol Res
. 2023 Jan;
11(3):339-350.
PMID: 36603132
The prolyl hydroxylase domain/hypoxia-inducible factor (PHD/HIF) pathway has been implicated in a wide range of immune and inflammatory processes, including in the oxygen-deprived tumor microenvironment. To examine the effect of...
4.
Inhaled dry powder cisplatin increases antitumour response to anti-PD1 in a murine lung cancer model
Davenne T, Percier P, Larbanoix L, Moser M, Leo O, Meylan E, et al.
J Control Release
. 2022 Dec;
353:317-326.
PMID: 36470334
Despite advances in targeted therapies and immunotherapy in lung cancer, chemotherapy remains the backbone of treatment in most patients at different stages of the disease. Inhaled chemotherapy is a promising...
5.
Vogel I, Acolty V, Keler T, Goriely S, Leo O, Moser M
Eur J Immunol
. 2022 Jul;
52(10):1620-1629.
PMID: 35856659
CD27/CD70 costimulation enhances T-cell survival, memory formation and Th1-cell differentiation and effector function. In addition to promoting Th1 responses, CD27 signaling has been shown to exert a negative regulatory role...
6.
Ajouaou Y, Azouz A, Taquin A, Denanglaire S, Hussein H, Krayem M, et al.
Elife
. 2022 Feb;
11.
PMID: 35192456
The oxygen sensor prolyl hydroxylase domain 2 (PHD2) plays an important role in cell hypoxia adaptation by regulating the stability of HIF proteins (HIF1α and HIF2α) in numerous cell types,...
7.
Papegay B, Nuyens V, Albert A, Cherkaoui-Malki M, Andreoletti P, Leo O, et al.
Liver Transpl
. 2020 Dec;
27(7):997-1006.
PMID: 33306256
Studies on how to protect livers perfused ex vivo can help design strategies for hepatoprotection and liver graft preservation. The protection of livers isolated from 24-hour versus 18-hour starved rats...
8.
Lepez A, Pirnay T, Denanglaire S, Perez-Morga D, Vermeersch M, Leo O, et al.
Sci Rep
. 2020 Dec;
10(1):21673.
PMID: 33303820
The AMP-activated kinase (AMPK) is a major energy sensor metabolic enzyme that is activated early during T cell immune responses but its role in the generation of effector T cells...
9.
Hussein H, Denanglaire S, Van Gool F, Azouz A, Ajouaou Y, El-Khatib H, et al.
Front Immunol
. 2020 Jan;
10:3007.
PMID: 31998303
RORγt-expressing Tregs form a specialized subset of intestinal CD4 Foxp3 cells which is essential to maintain gut homeostasis and tolerance to commensal microbiota. Recently, c-Maf emerged as a critical factor...
10.
Vamecq J, Papegay B, Nuyens V, Boogaerts J, Leo O, Kruys V
Biochimie
. 2019 Oct;
168:53-82.
PMID: 31626852
The occurrence of 3-methylglutaconic aciduria (3-MGA) is a well understood phenomenon in leucine oxidation and ketogenesis disorders (primary 3-MGAs). In contrast, its genesis in non-canonical (secondary) 3-MGAs, a growing-up group...