O E Dewit
Overview
Explore the profile of O E Dewit including associated specialties, affiliations and a list of published articles.
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Articles
5
Citations
47
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Recent Articles
1.
Deloose E, Depoortere I, de Hoon J, Van Hecken A, Dewit O, Vasist Johnson L, et al.
Neurogastroenterol Motil
. 2017 Aug;
30(1).
PMID: 28782145
Background: The gut hormone motilin stimulates gastrointestinal motility by inducing gastric phase III of the migrating motor complex (MMC) and enhancing the rate of gastric emptying. Camicinal (GSK962040), a small...
2.
Hobson R, Farmer A, Dewit O, ODonnell M, Hacquoil K, Robertson D, et al.
Neurogastroenterol Motil
. 2015 Sep;
27(11):1629-37.
PMID: 26348542
Background: A proportion of patients with foregut dysmotility fail to respond to standard interventions. Motilin agonists may be beneficial in this group. We aimed to determine the effect of camicinal,...
3.
Houghton L, Cremonini F, Camilleri M, Busciglio I, Fell C, Cox V, et al.
Neurogastroenterol Motil
. 2007 Aug;
19(9):732-43.
PMID: 17727393
Visceral hypersensitivity is important in the pathophysiology of irritable bowel syndrome and thus a target for modulation in drug development. Neurokinin (NK) receptors, including NK(3) receptors, are expressed in the...
4.
Willert R, Hobson A, Delaney C, Hicks K, Dewit O, Aziz Q
Aliment Pharmacol Ther
. 2007 Jan;
25(3):309-16.
PMID: 17217450
Background: Substance P acting via the neurokinin-1 receptor is involved in the development of hyperalgesia, although studies using neurokinin-1 receptor antagonists (NK-1RA) in human somatic pain have been disappointing. Aim:...
5.
Cremonini F, Houghton L, Camilleri M, Ferber I, Fell C, Cox V, et al.
Neurogastroenterol Motil
. 2005 Dec;
17(6):810-20.
PMID: 16336496
We assessed reproducibility of measurements of rectal compliance and sensation in health in studies conducted at two centres. We estimated samples size necessary to show clinically meaningful changes in future...