Nusa Krivec
Overview
Explore the profile of Nusa Krivec including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
78
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Recent Articles
1.
Lei Y, Duong M, Krivec N, Janssens C, Regin M, Huyghebaert A, et al.
Cell Prolif
. 2025 Feb;
:e13813.
PMID: 39908990
Chromosomal abnormalities acquired during cell culture can compromise the differentiation potential of human pluripotent stem cells (hPSCs). In this work, we identified a diminished differentiation capacity to retinal progenitor cells...
2.
Krivec N, Couvreu de Deckersberg E, Lei Y, Al Delbany D, Regin M, Verhulst S, et al.
Cell Death Dis
. 2024 Nov;
15(11):852.
PMID: 39572522
Gain of 1q is a highly recurrent chromosomal abnormality in human pluripotent stem cells. In this work, we show that gains of 1q impact the differentiation capacity to derivates of...
3.
Al Delbany D, Ghosh M, Krivec N, Huyghebaert A, Regin M, Duong M, et al.
Cells
. 2024 Aug;
13(16).
PMID: 39195283
Human pluripotent stem cells (hPSCs) are pivotal in regenerative medicine, yet their in vitro expansion often leads to genetic abnormalities, raising concerns about their safety in clinical applications. This study...
4.
Lei Y, Al Delbany D, Krivec N, Regin M, Couvreu de Deckersberg E, Janssens C, et al.
Stem Cell Reports
. 2024 Mar;
19(4):562-578.
PMID: 38552632
Human pluripotent stem cell (hPSC) cultures are prone to genetic drift, because cells that have acquired specific genetic abnormalities experience a selective advantage in vitro. These abnormalities are highly recurrent...
5.
Krivec N, Ghosh M, Spits C
Stem Cell Reports
. 2023 Dec;
19(1):11-27.
PMID: 38157850
The genetic abnormalities observed in hPSC cultures worldwide have been suggested to pose an important hurdle in their safe use in regenerative medicine due to the possibility of oncogenic transformation...
6.
Keller A, Krivec N, Markouli C, Spits C
Methods Mol Biol
. 2022 May;
2429:57-72.
PMID: 35507155
Human pluripotent stem cells have a wide variety of potential applications, ranging from clinical translation to in vitro disease modeling. However, there is significant variation in the potential of individual...
7.
Ljubetic A, Lapenta F, Gradisar H, Drobnak I, Aupic J, Strmsek Z, et al.
Nat Biotechnol
. 2017 Oct;
35(11):1094-1101.
PMID: 29035374
Polypeptides and polynucleotides are natural programmable biopolymers that can self-assemble into complex tertiary structures. We describe a system analogous to designed DNA nanostructures in which protein coiled-coil (CC) dimers serve...