Nuria Lloberas
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Explore the profile of Nuria Lloberas including associated specialties, affiliations and a list of published articles.
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62
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799
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Recent Articles
11.
and Cluster Polymorphism Effects on LCP-Tac Tacrolimus Exposure: Population Pharmacokinetic Approach
Mohammed Ali Z, Meertens M, Fernandez B, Fontova P, Vidal-Alabro A, Rigo-Bonnin R, et al.
Pharmaceutics
. 2023 Dec;
15(12).
PMID: 38140040
The aim of the study is to develop a population pharmacokinetic (PopPK) model and to investigate the influence of CYP3A5/CYP3A4 and ABCB1 single nucleotide polymorphisms (SNPs) on the Tacrolimus PK...
12.
Rigo-Bonnin R, Rossello-Palmer E, Sanchez-Garcia A, Pallares-Borras M, Martinez Y, Videla S, et al.
Clin Chim Acta
. 2023 Sep;
549:117554.
PMID: 37704005
Background: Apixaban's technical sheet does not recommend its use in clinical practice for patients with chronic kidney disease undergoing haemodialysis. However, recent studies indicate that apixaban could be a safe...
13.
Lloberas N, Grinyo J, Colom H, Vidal-Alabro A, Fontova P, Rigo-Bonnin R, et al.
Kidney Int
. 2023 Jun;
104(4):840-850.
PMID: 37391040
For three decades, tacrolimus (Tac) dose adjustment in clinical practice has been calculated empirically according to the manufacturer's labeling based on a patient's body weight. Here, we developed and validated...
14.
Fontova P, van Merendonk L, Vidal-Alabro A, Rigo-Bonnin R, Cerezo G, Van Oevelen S, et al.
Pharmaceutics
. 2023 May;
15(5).
PMID: 37242723
Despite intensive monitoring of whole blood tacrolimus concentrations, acute rejection after kidney transplantation occurs during tacrolimus therapy. Intracellular tacrolimus concentrations could better reflect exposure at the site of action and...
15.
Lalagkas P, Iliou J, Rigo R, Miarons M, Fernandez-Alarcon B, Bestard O, et al.
Clin Pharmacokinet
. 2023 May;
62(6):861-880.
PMID: 37140726
Background And Objective: The gold standard treatment of established cytomegalovirus infection or prevention in solid organ transplantation is the intravenous administration of ganciclovir (GCV) or oral administration of valganciclovir (VGCV),...
16.
Crespo E, Vidal-Alabro A, Jouve T, Fontova P, Stein M, Mocka S, et al.
Front Immunol
. 2022 Jul;
13:869554.
PMID: 35833145
Achieving fast immunosuppression blood exposure after kidney transplantation is key to abrogating both preformed and anti-donor humoral and cellular alloresponses. However, while tacrolimus (TAC) is the cornerstone immunosuppressant inhibiting adaptive...
17.
Anton-Pampols P, Diaz-Requena C, Martinez-Valenzuela L, Gomez-Preciado F, Fulladosa X, Vidal-Alabro A, et al.
Int J Mol Sci
. 2022 Apr;
23(8).
PMID: 35457026
The inflammasome is an immune multiprotein complex that activates pro-caspase 1 in response to inflammation-inducing stimuli and it leads to IL-1β and IL-18 proinflammatory cytokine production. NLRP1 and NLRP3 inflammasomes...
18.
Simon-Molas H, Vallve-Martinez X, Caldera-Quevedo I, Fontova P, Arnedo-Pac C, Vidal-Alabro A, et al.
Int J Mol Sci
. 2021 Jul;
22(14).
PMID: 34299056
The glycolytic modulator TP53-Inducible Glycolysis and Apoptosis Regulator (TIGAR) is overexpressed in several types of cancer and has a role in metabolic rewiring during tumor development. However, little is known...
19.
Guiteras J, Ripoll E, Bolanos N, de Ramon L, Fontova P, Lloberas N, et al.
Mol Ther Nucleic Acids
. 2021 May;
24:807-821.
PMID: 33996261
Systemic lupus erythematosus is a highly complex and heterogeneous autoimmune disease mostly mediated by B cells. It is characterized by circulating self-reactive antibodies that deposit and form immune complexes in...
20.
Esquius L, Javierre C, Llaudo I, Rama I, Oviedo G, Massip-Salcedo M, et al.
Int J Environ Res Public Health
. 2021 Apr;
18(8).
PMID: 33919722
Physical exercise is known to have a dose-dependent effect on the immune system and can result in an inflammatory process in athletes that is proportional to the intensity and duration...